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  • 1,10100lei 990.00 lei


    Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team.
    Features: • Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information.
    • Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors.
    • Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance).
    • Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches.
    • Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases.
    New To This Edition:

    • Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT).
    • New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section.
    • Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes.
    • Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors.
    • Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current.
    • Disease Site chapters feature updated information on disease management and outcomes.
    • Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma.
    • Thirty all-new anatomy drawings increase your visual understanding.
    • Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

  • 992.00 lei

    From The New England Journal of Medicine, February 24, 2000
    As Pui comments in the preface, the need for this book is based on the relative paucity of books in which all aspects of childhood leukemias are collated, despite the rapid expansion of sci

  • 1,10600lei 995.00 lei

    The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine.  

    The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in proteome. Newer assays that allow greater stability and analytical consistency are emerging. These alterations in tumor profiles can be also now detected by imaging techniques.

    The heterogeneity of both tumor and tumor microenvironment, an inevitable reality, is discussed in detail with particular focus on cancer stem cells and immune signaling. A chapter is dedicated  to the emerging technology of “liquid biopsy”, which opens a novel approach for “continuous” monitoring of cancer that might be superior to conventional diagnostics,

    “Molecular Pathology of Breast Cancer” provides a quick and easy, not to mention essential, tour for clinicians, pathologists and scientists who are seeking to understand the integration of molecular biology into the diagnosis, prognosis and management of breast cancer.

  • 1,10000lei 1000.00 lei

    Transfusion medicine as a multidisciplinary clinical specialty allied to blood banking continues to be a dynamic and increasingly complex evolution. Patients who require blood transfusions generally fall into two categories: those requiring transfusions resulting from acute blood loss that might be associated with surgery or accident; or those requiring chronic transfusions associated with treatment for chronic anaemias, chemotherapy, or bone marrow transplant. As such transfusion medicine impacts all areas of critical care medicine, and multiple areas of chronic care. Rossi′s Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available. Now updated for a fifth edition with new material on donor care including the frequency of donation and management of iron deficiency/status, patient blood management, hemovigilance, and the novel cellular therapies and stem cell transplantation. This is a key resource for specialists and trainees in transfusion medicine and blood banking, as well as physicians, nurses, and medical technologists active in the transfusion of patients. This edition; Compiled by a world class Editor team including two past–presidents of AABB, a past– President of the American Board of Pathology and members of the FDA Blood Products Advisory Committee, and international contributor team Covers current hot topics such as donor care including the frequency of donation and management of iron deficiency/status), patient blood management, hemovigilance, and the organization of transfusion and transplant services Presents new material on molecular immunohematology Companion website includes figures, full text and references Update your practice with this comprehensive reference resource, considered the gold standard in transfusion medicine.

  • 1000.00 lei

    Features · Encompasses all aspects from basic science (anatomy and physiology) to clinical aspects of diagnosis and treatment of peritoneal cancer · Features editors who are leading figures in the field of intraperitoneal cancer with chapters contributed by an international team of experts from North America, Europe, and elsewhere · Discusses the latest advances in the rapidly growing field of intraperitoneal cancer therapy · Appeals both to clinical oncologists (surgical, gynecological, and medical) and researchers seeking a reliable and up-to-date reference Summary Intraperitoneal Cancer Therapy: Principles and Practice is one of the first books to combine the latest clinical developments in the treatment of patients with peritoneal surface disease and the scientific principles that underlie the concept of intraperitoneal cancer therapy. The book covers basic concepts such as anatomy, physiology, pharmacology, and mathematical models of drug transport as well as practical clinical applications, highlighted with results from clinical trials and promising novel preclinical developments. The book is a state-of-the-art reference for surgical and medical oncologists interested in the treatment of carcinomatosis. It also establishes and promotes basic and translational research interest in the field of intraperitoneal drug delivery, which has the potential to improve the outcome for this dreaded condition. Edited by two renowned surgical oncologists, it represents the definitive reference in the field of intraperitoneal cancer therapy.

  • 1,12600lei 1015.00 lei

    Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners comprehensively addresses all aspects of clinical management for cancer taking a balanced, authoritative and, -where possible- evidence-based stance and may be used in conjunction with the book, The American Cancer Society's Principles of Oncology: Prevention to Survivorship. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a practical understanding of the field of oncology.

  • 1,05500lei 1025.00 lei

    Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients.
    • A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease 
    • An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies
    • Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics
    • Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs
    • Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

  • Breast Disease
    La comanda in aproximativ 4 saptamani
    1,18300lei 1030.00 lei

    This second volume of the handbook on breast disease provides a comprehensive overview of its clinical management and current therapies. It brings readers up to speed with the latest guidelines and therapeutic regimens in breast cancer and provides and in-depth account of current and new therapeutic approaches.

    Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget’s disease and phyllodes tumors, and a section on supportive and follow-up care.

    By adopting a multidisciplinary approach to breast cancer, this book is a must- have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

  • 1,23500lei 1100.00 lei

     For more than 30 years, Perez and Brady's Principles and Practice of Radiation Oncology has been the must-have standard reference for radiation oncologists and radiation oncology residents who need a comprehensive text covering both the biological and physical science aspects of this complex field as well as disease site-specific information on the integrated, multidisciplinary management of patients with cancer.

    The book has established itself as the discipline’s "text-of-record," belonging on the shelf of all of those working in the field. The Seventh Edition continues this tradition of excellence with extensive updates throughout, many new chapters, and more than 1,400 full-color illustrations that highlight key concepts in tumor pathogenesis, diagnosis, and targeted radiation therapy.

             Comprehensive coverage of the current state of knowledge of cancer biology; medical radiation physics; clinical radiation oncology; and radiation oncology economics, ethics, and public policy.

             Regular, twice-yearly content updates available with the digital version of the text.

             Ideal for radiation oncologists, radiation oncology residents, radiation biologists, medical radiation physicists, oncologists, physicists-in-training, radiation dosimetrists, and nurses and physician assistants working in radiation oncology departments.

             New chapters include: Proton and Carbon Ion Beam Dosimetry and Treatment Planning; Stereotactic Radiation Therapy; Re-Irradiation; Error Avoidance; Undergraduate, Graduate, and Continuing Medical Education in Radiation Oncology; and a completely rewritten chapter on the economics of radiation oncology.

             Designed to provide a better understanding of the natural history of cancer, the physical and technological methods of radiation application, the effects of irradiation on normal tissues, and the most judicious ways in which radiation therapy can be employed in the treatment of patients with cancer, either as a single modality or as part of a multi-modality treatment program.

             All references printed in the book are now streamlined for quick access to further information.

             Site-specific chapters include relevant background information on each tumor—including epidemiology, pathology, diagnostic work-up, prognostic factors, treatment techniques, applications of surgery, chemotherapy, immunotherapy and biological therapy, end results, and more.

             Increased focus on new approaches and technologies with new and updated chapters.

             Greater emphasis on palliative and supportive care reflects the role of radiation treatment in non-curative roles.

             An international group of expert chapter authors keeps you well-informed.

             A completely revised first chapter is designed to provide an overview of the discipline of radiation oncology. This will be particularly useful for residents beginning training and medical students beginning a radiation oncology clinical clerkship. The chapter is supplemented with multiple sidebars to augment the reader's understanding of the field.

            

    Enrich Your Ebook Reading Experience with Enhanced Video, Audio and Interactive Capabilities!

             Read directly on your preferred device(s), such as computer, tablet, or smartphone

             Customize for your language, including right-to-left reading, vertical writing, and enhanced annotation in over 30 languages

             Easily convert to audiobook, powering your content with natural language text-to-speech

             Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more

  • Cancer of the Head and Neck, 5e
    La comanda in aproximativ 4 saptamani
    1,35000lei 1200.00 lei

    More than 52,000 head and neck cancers are diagnosed each year in the US alone.  The leading causes of these cancers include tobacco and alcohol use and infections with HPV.  Treatment usually involves surgery, radiation therapy and chemotherapy, which involves a team of physicians from each of these areas.  While this text is multi-disciplinary, it is written by head and neck surgeons with a primary focus on the surgical aspects of treatment for otolaryngologists and trainees.  Generally considered a definitive and classic reference in the field; this book provides comprehensive coverage of everything from basic science to treatment and rehabilitation.

    Key Features

    ·         Classic and established text in the field

    ·         Comprehensive coverage from basic science to treatment and rehabilitation

    ·         Extensive revisions to cover new techniques and topics since fourth edition

    ·         Multidisciplinary with focus on the surgical aspects of treatment

    ·         New color photographs and drawings throughout

    ·         Written and edited exclusively by and for head and neck surgeons

    Chapter 1 Perspectives in Cancer of the Head and Neck 
    Eugene N. Myers

    Chapter 2 Pathogenesis and Progression of Squamous Cell Carcinoma of the Head and Neck 
    Ryan M. Aronberg, Natalia Issaeva, and Wendell G. Yarbrough

    Chapter 3 Pathology of the Head and Neck: Basic Considerations and New Concepts 
    Elizabeth G. Demicco and Bruce M. Wenig

    Chapter 4 Epidemiology, Demographics/Disparity 
    Stacey A. Fedewa and Amy Y. Chen

    Chapter 5 Imaging of Head and Neck Cancer 
    Reza Forghani, Jason M. Johnson, and Lawrence E. Ginsberg

    Chapter 6 Anesthetic Management for Head and Neck Cancer Surgery 
    A ngela Truong and Dam-Thuy Truong

    Chapter 7 Head and Neck Cancer Care: Quality Guidelines 
    Carol M. Lewis, Amy C. Hessel, Stephen Y. Lai, and Randal S. Weber

    Chapter 8 Nonmelanoma Skin Cancer 
    Malcolm A. Buchanan, Carsten E. Palme, Faruque Riffat, and Michael J. Veness

    Chapter 9 Melanoma of the Head and Neck 
    Cecelia E. Schmalbach, Alison B. Durham, Timothy M. Johnson, and Carol R. Bradford

    Chapter 10 Cancer of the Nasal Cavity and the Paranasal Sinuses 
    Ehab Y. N. Hanna, Shirley Su, Michael E. Kupferman, Shaan M. Raza, and Franco DeMonte

    Chapter 11 Nasopharyngeal Carcinoma 
    Brigette B. Y. Ma, Michael K. M. Kam, and Anthony T. C. Chan

    Chapter 12 Cancer of the Lip 
    Jessica J. Peck, Daniel Petrisor, and Mark K. Wax

    Chapter 13 Squamous Cell Cancer of the Oral Cavity 
    Laureano A. Giraldez-Rodriguez, Brett Miles, and Eric M. Genden

    Chapter 14 Cancer of the Oropharynx 
    David M. Neskey, Katherine A. Hutcheson, and Michael E. Kupferman

    Chapter 15 Cancer of the Larynx 
    Richard O. Wein, Kathryn A. Gold, G. Brandon Gunn, and Randal S. Weber

    Chapter 16 Cancer of the Hypopharynx and Cervical Esophagus 
    Parul Sinha and Bruce H. Haughey

    Chapter 17 Tumors of the Cervical Trachea 
    Ralph W. Gilbert and Shaf Keshavjee

    Chapter 18 Cancer of the Neck 
    Jesus E. Medina

    Chapter 19 Thyroid Cancer 
    Jennifer R. Cracchiolo and Ashok R. Shaha

    Chapter 20 Tumors of the Parathyroid Gland 
    Katrina Chaung, William S. Duke, and David J. Terris

    Chapter 21 Cancer of the Salivary Glands 
    Yekaterina A. Koshkareva and Robert L. Ferris

    Chapter 22 Tumors of the Parapharyngeal Space 
    Zhen Gooi, Matthew J. Kruse, David W. Eisele, and Jeremy D. Richmon

    Chapter 23 Ear and Temporal Bone Cancer 
    Paul W. Gidley

    Chapter 24 Cancer of the Head and Neck in the Pediatric Population 
    Catherine G. Lam, Atmaram Pai Panandiker, Jon P. Ver Halen, Noah D. Sabin, and Sandeep Samant

    Chapter 25 Head and Neck Cancer in Developing Countries 
    Johan Fagan and Clare Stannard

    Chapter 26 Lymphomas Presenting in the Head and Neck: Current Issues in Diagnosis and Management 
    Chan Yoon Cheah and Fredrick B. Hagemeister

    Chapter 27 Sarcomas and Soft Tissue Tumors of the Head and Neck 
    Marcus M. Monroe, Beverly A. Guadagnolo, Vinod Ravi, Wei-Lien Wang, and Erich M. Sturgis

    Chapter 28 Reconstruction of Major Defects in the Head and Neck Following Cancer Surgery 
    Jerry Castro, Cathy Lazarus, Daniel Buchbinder, Adam Jacobson, Devin Okay, Joseph Dayan, Ilya Likhterov, and Mark L. Urken

    Chapter 29 Oral and Maxillofacial Rehabilitation of Patients with Head and Neck Cancer 
    Richard C. Cardoso, Theresa M. Hofstede, Patricia C. Montgomery, Jack W. Martin, Adam S. Garden, Ruth A. Aponte-Wesson, Alexander M. Won, and Mark S. Chambers

    Chapter 30 General Principles of Radiation Therapy for Cancer of the Head and Neck 
    Randall J. Kimple, Bhishamjit S. Chera, and Paul M. Harari

    Chapter 31 Chemotherapy in the Treatment of Squamous Cell Carcinoma of the Head and Neck 
    Nabil F. Saba and Fadlo R. Khuri

    Chapter 32 Cancer of the Head and Neck: Targeted Molecular Therapy of Head and Neck Cancer 
    Katharine A. Price, Rafael Santana-Davila, Laura Q. M. Chow, Cesar A. Perez, Garrett Green, Loren K. Mell, and Ezra E. W. Cohen

    Chapter 33 Rehabilitation of Swallowing and Speech in Patients Treated for Cancer of the Head and Neck 
    Jan S. Lewin

    Chapter 34 Supportive and Palliative Care 
    A hmed Elsayem and Eduardo Bruera

    Chapter 35 Quality of Life in Head and Neck Cancer 
    A llen C. Sherman and Stephanie Simonton-Atchley

    Chapter 36 Application of Advances in Endoscopic and Robot-Assisted Approaches to the Treatment of Head and Neck Cancer 
    Jason G. Newman and Bert W. O’Malley Jr.

    Chapter 37 Hemangiomas and Vascular Malformations of the Head and Neck 
    James Y. Suen and Gresham T. Richter

  • 1,35100lei 1215.00 lei

    A resource that combines oncologic principles with treatment plans for the surgical management of neoplasms

    Textbook of General Surgical Oncology is a practical and comprehensive reference that offers authoritative coverage of a wide variety of oncologic concepts and disorders. The book opens with detailed discussion of the general principles of molecular biology, cancer epidemiology, surgical oncology, radiation oncology, medical oncology, immunotherapy, nuclear imaging, and molecular diagnostics.  The text then focuses on site-specific neoplasms, such as those of the skin, soft tissue, bone, head/neck, brain, lung, mediastinum, breast, pleura, peritoneum, as well as tumors that affect various systems, including the endocrine, gastrointestinal, hepatobiliary, genitourinary, gynecologic, and hematopoietic.

    ·        Each chapter is written by an internationally recognized expert on the topic

    ·        Learning aids include chapter-ending Q&A and Practical Pearls

    ·        Outstanding review for the new General Surgical Oncology certification examination

    This new textbook addresses an interesting topic, that is, “complex” surgical oncology. This term, a relatively new one in the lexicon of cancer management, refers to those complicated procedures that tend to be centralized and performed by experienced surgeons. However, there is much more here than complex procedures.

    The book is in an interesting format. The section editors are a “who's who” of the surgical oncological leadership. The editors have gathered together a collection of international and national authors, all part of the emerging leadership in surgical oncology—a most enlightened approach. Many of the authors are young, actively involved, and part of the development of a new cadre of surgeons focused on oncology. There is, however, a smattering of seniors who have not yet reached their “use by date.” All of these provide a comprehensive text.

    Somewhat politically correct, the book avoids the concern that, as the majority of cancer surgery is per-formed in the United States by general surgeons, no attempt is made to confuse the issue of just what constitutes a complex cancer operation that should be done by a surgical oncologist. The text, 165 chapters, addresses much more than the principles of complex surgical oncology. The chapters include what might be considered standard procedures, particularly in breast and colon, readily performed by well-trained surgeons. It does provide for all surgeons the indications, roles, and efficacy of adjuvant therapy, both pre- and post-operatively.

    As always, trying to be all things to all people provides certain challenges. Many of the chapters adhere to conventional approaches without prediction but are well balanced. There is enough to generate controversy, always a good thing. In this writer's opinion the willingness to address over diagnosis, over investigation, and over treatment is a welcome emergence, albeit hesitatingly. In an age where much of oncologic management is defined and provided by online access, this text will provide a comprehensive source readily searchable for individual topics.

    As we move further into the 21st century, we must emphasize that cancer care is a multidisciplinary approach and a dynamic process. The Textbook of Complex General Surgical Oncology is constructed to serve as a comprehensive resource for clinicians treating cancer patients. The focus of this book is to ensure discussion of core principles as well as to provide guidance in the management of various cancer sites and types. The initial aspect of the book contains an overview of germane general concepts while the vast majority comprises sections categorized as breast, endocrine, gastrointestinal, head and neck, hepatobiliary, melanoma and other cutaneous malignancies, pancreatic, peritoneal, sarcoma and other soft tissue neoplasms, reconstruction, and thoracic.

    Surgical oncology is now recognized by the American Board of Surgery as a distinct specialty of general surgery. This textbook is primarily written by contributors who have been formally trained in surgical oncology. The strength lies in the ensemble of world-class thought leaders who have offered their unparalleled expertise within their niche. Every effort has been made to include institutions from all aspects of the globe.

    It is beyond the scope of this book to include every cancer, as surgical oncologists typically do not manage tumors encompassing the hematopoietic, neurologic, orthopedic, genitourinary, or gynecologic systems. However, it is the intent of the editors that any health-care provider who seeks to learn more about surgical oncology utilize this book as we acknowledge that most operations today on cancer patients are performed by general surgeons.

    Table of Contents

    Part I. Oncologic Concepts

    1. Molecular Biology
    2. Cancer Epidemiology
    3. Cancer Genetics
    4. Surgical Oncology
    5. Radiation Oncology
    6. Medical Oncology
    7. Immunotherapy
    8. Nuclear Imaging
    9. Molecular Diagnostics

    Part II. Oncologic Disorders

    10. Skin Neoplasms
    11. Soft Tissue Neoplasms
    12. Neoplasms of the Bone
    13. Head and Neck Cancer
    14. Neoplasms of the Brain
    15. Lung Cancer
    16. Neoplasms of the Mediastinum
    17. Breast Cancer
    18. Neoplasms of the Pleura
    19. Neoplasms of the Peritoneum
    20. Neoplasms of the Endocrine System
    21. Neoplasms of the Gastrointestinal Tract
    22. Neoplasms of the Hepatobiliary Tree
    23. Neoplasms of the Genitourinary System
    24. Neoplasms of the Gynecologic System
    25. Neoplasms of the Hematopoietic System

  • 1,38600lei 1230.00 lei

     The consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists and others who treat cancer patients, Cancer Medicine 8 covers the ever-widening sphere of current cancer knowledge and clinical practice. In this new 8th edition an outstanding editorial team from world-renowned medical centers continues to hone the leading edge forged in previous editions, with timely information on biology, immunology, etiology, epidemiology, prevention, screening, pathology, imaging and therapy. The book is a testament to the editorial panel's creed that innovative, comprehensive, multidisciplinary treatment of cancer patients must be grounded in a fundamental understanding of cancer biology. Cancer Medicine 8 does a superb job of bringing scientific principles into clinical practice. This text is the ultimate resource of new information providing the basis for better informed cancer therapy choices. Cancer Medicine 8 features hundreds of 4-color illustrations, photographs, tables, graphs and algorithms that make this text an invaluable clinical tool in recognizing characteristic appearances of both patient and tissue. The 137 tightly focused chapters are organized into 5 sections: I: Cardinal Manifestations of Cancer II: Scientific Foundations of Cancer III: Principles of Cancer Diagnosis IV: Principles of Therapeutic Modalities V: Principles of Multidisciplinary Management Major Revisions: Chapter 6: Oncogenes An entire section is devoted to oncogenes like kit, Ret, Braf, Akt genes and the new drugs that specifically target them. This chapter not only provides a list of these new therapies but also insight as to how they target the oncogenes and their mutations, as well as therapy response and efficacy. Chapter 11: Tumor Angiogenesis This chapter provides a wealth of new data and understanding of the mechanisms of angiogenesis and how it contributes to the malignancy of various cancers The Clinical Advancement section provides an extensive summary of new trials investigating numerous novel angiogenesis agents Chapter 33: Chemoprevention This chapter also provides a considerable amount of new information for a broad range of clinical trials such as the HPV vaccine trial Future, Select, Star, Approve and PreSAP. The rationales for these trials are discussed and resulting data from the completed trials are presented. Chapter 55: Cytokines Research on cytokines is another area that is exploding in magnitude. This chapter presents a wealth of new information on promising new therapeutic agents.There is also updated information on the therapeutic usage of currently available agents such as hemotopoietic growth factors (HGF), erythropoietin and thromobopoietic agents. Chapter 56: Monoclonal Serotherapy A considerable amount of research has been done in the past few years on therapeutic and targeted agents in cancer therapy. Updated information and data is provided from recent trials for therapies previously discussed in Cancer Medicine edition 7 covering therapeutic agents and targeted toxins. Chapter 77: Neoplasms of the Head and Neck There is a discussion of changes in treatment methods for certain cancers such as the recent shift from surgery to combined chemotherapy with radiotherapy for tonsillar cancer, nasal and paranasal sinuses cancers and laryngeal cancer. Chapter 78: Lung Cancer Advances in diagnostic techniques are described such as ultrasound-guided fine needle aspiration or electromagnetic navigation diagnostic bronchoscopy. Video assisted thoracoscopic surgery 

  • 1,38000lei 1245.00 lei

    DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. -Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. - Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. - Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. - Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. - Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues

  • 1,39100lei 1255.00 lei

    Now in a single, convenient volume, The Breast: Comprehensive Management of Benign and Malignant Diseases, 5th Edition covers every clinically relevant aspect of the field: cancer, congenital abnormalities, hormones, reconstruction, anatomy and physiology, benign breast disease, and more. Building upon the strengths of previous editions, this updated volume by Drs. Kirby I. Bland, Edward M. Copeland III, V. Suzanne Klimberg, and William J Gradishar, includes the latest innovations in breast cancer detection and treatment in a practical, easy-to-use format ideal for today’s surgeons.

    New to this edition
    • Offers the most comprehensive, up-to-date information on the diagnosis and management of, and rehabilitation following, surgery for benign and malignant diseases of the breast.
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    • Covers the latest developments in receptor modulation, targeted monoclonal antibodies, evolving inhibitors with triple-negative disease, and more.
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    • Discusses recent minimally invasive surgical techniques and new developments in oncoplastic breast conservation techniques.
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    • Contains significant updates to the "Management of Systemic Disease" section that reflect the latest advances in chemotherapy, hormonal resistance, and therapy.
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    • Includes links to real-time procedure videos and full-color procedural line drawings from the Klimberg Atlas of Breast Surgical Techniques on Expert Consult, providing expert visual guidance on how to execute key steps and techniques.
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    • Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.

  • 1,34500lei 1260.00 lei

     The understanding of diagnostic lymph node and spleen pathology has evolved at an impressive pace since 1995, when the third series AFIP atlas was published. Progress has been fueled, in large part, by the application of a number of technologies to the study of hematopoietic neoplasms. The World Health Organization (WHO) classification scheme for hematologic neoplasms has captured much of this progress, and is generally accepted for clinical practice. The current volume, part of the fourth series of atlases, integrates the WHO classification, including the 2016 revision, and highlights areas in which the WHO classification is likely to evolve with time.

    In keeping with the goals and tradition of the atlases, this volume emphasizes morphological features of hematopoietic neoplasms, and includes a discussion of differential diagnoses for each disease category. In addition, the results of immunophenotypic and molecular genetic testing for each disease are highlighted, including findings generated by using high-throughput techniques that likely will be integrated into standard diagnostics in the near future.

    Overall, the Tumors of the Lymph Node and Spleen atlas will provide readers with the comprehensive information necessary for the pathological and clinical assessment of lymph node and splenic lesions.

    Order the Tumors of the Lymph Node and Spleen AFIP atlas now to take advantage of these new discoveries and techniques for diagnosing and treating these types of tumors.

  • 1,49000lei 1320.00 lei

    Oral, Head and Neck Oncology and Reconstructive Surgery By R. Bryan Bell, DDS, MD, FACS; Peter A. Andersen, San Diego State University, California, U.S.A. and Rui Fernandes, DMD, MD

    Description: Oral, Head and Neck Oncology and Reconstructive Surgery is the first oral and maxillofacial surgery (OMS) text to provide you with a system for managing adult oral, head and neck cancers and reconstructive cranio-maxillofacial surgery. Using an evidence-based approach to the management and treatment of a wide variety of clinical conditions, the extensive experience of the author and contributors in head and neck/cranio-maxillofacial surgery and oncology are highlighted throughout the text.
    This includes computer aided surgical simulation, intraoperative navigation, robotic surgery, endoscopic surgery, microvascular surgery, molecular science, and tumor immunology. In addition, high quality photos and illustrations are accompanied by videos of surgical procedures that are easily accessible on mobile devices.

    New To This Edition:
    • Management protocols and outcomes assessment provide clear guidelines for managing problems related to adult head and neck oncology and reconstructive cranio-maxillofacial surgery.
    • State-of-the art guidance by recognized experts details current techniques as well as technological advances in head and neck/cranio-maxillofacial surgery and oncology.
    • Evidence-based content details the latest diagnostic and therapeutic options for treating a wide-variety of clinical problems with an emphasis on surgical technique and outcomes.
    • Multidisciplinary approach reflects best practices in managing head and neck oncology and cranio-maxillofacial surgery.
    • 900 highly detailed images clearly demonstrate pathologies and procedures.
    • Designed for the modern classroom which lets you access important information anywhere through mobile tablets and smart phones.

    Table Of Contents:

    Unit 1: PRINCIPLES

    Chapter 1. Epidemiology for non-HPV-Related Oral, Head and Neck Cancer/Etiology
    Chapter 2. Cellular and Molecular Pathology
    Chapter 3. The Molecular Landscape of Head and Neck Squamous Cell Carcinoma
    Chapter 4. Oncoviruses
    Chapter 5. Diagnostic Imaging
    Chapter 6. Endoscopic Evaluation of the Upper Aerodigestive Tract
    Chapter 7. Computer Aided Head and Neck Surgery
    Chapter 8. Navigation in Head and Neck Tumor Surgery
    Chapter 9. Management of the Neck/Sentinel Lymph Node Biopsy
    Chapter 10. Microvascular Surgery in Head and Neck Cancer Reconstruction
    Chapter 11. Mandibular and Maxillary Reconstruction Using In-Situ Tissue Engineering
    Chapter 12. Dental Implant Supported Prosthetic Rehabilitation
    Chapter 13. Radiation Oncology
    Chapter 14. Chemotherapy
    Chapter 15. Immunotherapy for Head and Neck Cancer
    Chapter 16. Oral/Dental Oncology
    Chapter 17. Speech Pathology and Rehabilitation

    Unit 2: SITE-SPECIFIC MULTIDISCIPLINARY TREATMENT

    Section 1: ORAL CAVITY
    Chapter 18. Management of T1-T2 Oral Tongue Squamous Cell Carcinoma
    Chapter 19. Management of T3 Oral Tongue Squamous Cell Carcinoma: Hemiglossectomy with Free Flap Reconstruction
    Chapter 20. (T4 Oral Tongue Tumors) Total Glossectomy with Free Flap Reconstruction
    Chapter 21. Management of T1 Floor of Mouth Squamous Cell Carcinoma: Floor of Mouth Resection with Sialodochoplasty
    Chapter 22. Oral cavity (T2 Floor of mouth): Anterior floor of mouth resection with reconstruction
    Chapter 23. Oral cavity (T1-T2 Mandibular gingiva): Composite resection with marginal mandibulectomy with and without reconstruction
    Chapter 24. Oral cavity (T3-4 Mandibuar gingiva):Compostie resection of floor of mouth and mandible with free flap
    Chapter 25. Oral Cavity: (T1-T2 Buccal Mucosa): Wide Excision with and Without Reconstruction
    Chapter 26. Oral cavity: (T3-T4 buccal mucosa): Wide excision and reconstruction with free flap
    Chapter 27. Oral cavity :(T1-T2 Maxillary gingiva): Infrastructure Maxillectomy with and without reconstruction
    Chapter 28. Oral cavity: (T3-T4 Maxillary gingiva): Maxillectomy with and without orbital involvement and reconstruction
    Chapter 29. Management of T4 Maxillary Gingiva Squamous Cell Carcinoma (Total Maxillectomy with Reconstruction)
    Chapter 30. T4 Maxillary Gingival Carcinoma with Nasal Involvement
    Chapter 31. Management of T1-T3 Squamous Cell Carcinoma of the Lip: Lip Excision and Local Flap Reconstruction

    Section 2: OROPHARYNX
    Chapter 32. Management Of Early Stage (T1-T2) Tonsillar Carcinoma
    Chapter 33. Oropharynx (T3-T4 Tonsil): Surgical and non-surgical management
    Chapter 34. Oropharynx (T1-T2 Base of tongue): Surgical and non-surgical management
    Chapter 35. Oropharynx (T3-T4 Base of tongue): Surgical and non-surgical management
    Chapter 36. Contemporary Management of Oral Head and Neck Squamous Cell Carcinoma: Oropharynx (Soft palate): Surgical and Non-Surgical Management

    Section 3: LARYNX
    Chapter 37. Larynx (T1-T2 Supraglottic larynx): Surgical and non-surgical management
    Chapter 38. Larynx (T3-T4 Supraglottic larynx): Surgical and non-surgical management
    Chapter 39. Larynx (T1-T2 Glottic larynx): Surgical and non-surgical management
    Chapter 40. Larynx (T3-T4 Glottic larynx): Surgical and non-surgical management
    Chapter 41. Larynx (Subglottic larynx): Surgical and non-surgical management
    Chapter 42. Salivary gland cancer
    Chapter 43. Melanoma
    Chapter 44. Aggressive skin cancer: Surgical and non-surgical management
    Chapter 45. Management of Osteoradionecrosis

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    Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer.

    Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment.

    A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care.

    The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.

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    Written by the leading names in pediatric oncology and hematology, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color, two-volume set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski’s is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.

  • Oxford Textbook of Palliative Medicine
    La comanda in aproximativ 4 saptamani
    1400.00 lei

    The definitive Oxford Textbook of Palliative Medicine, now in its fifth edition, has again been thoroughly updated to offer a truly global perspective in this field of extraordinary talent and thoughtfulness. 
     
    Updated to include new sections devoted to assessment tools, care of patients with cancer, and the management of issues in the very young and the very old, this leading textbook covers all the new and emerging topics since its original publication in 1993. In addition, the multi-disciplinary nature of palliative care is emphasized throughout the book, covering areas from ethical and communication issues, the treatment of symptoms and the management of pain. 
     
    The print edition comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables, ensuring this edition continues to be at the forefront of palliative medicine. 
     
    This fifth edition of the Oxford Textbook of Palliative Medicine is dedicated to the memory of Professor Geoffrey Hanks, pioneer in the field of palliative medicine, and co-editor of the previous four editions. A truly comprehensive text, no hospital, hospice, palliative care service, or medical library should be without this essential source of information.

  • 1,76400lei 1411.00 lei

    1764 RON 1411 RON

    Now thoroughly updated to include new advances in the field, Principles and Practice of Pediatric Oncology, 7th Edition remains the gold standard text for the care and research of children with cancer. This authoritative reference is the single most comprehensive resource on the biology and genetics of childhood cancer as well as its diagnosis, multimodal treatment, as well as long-term management of young patients with cancer. Also addressed are a broad array of topics on the supportive and psychosocial aspects of care of children and families. Covering virtually every aspect of the breadth and depth of childhood cancer, this 7th Edition provides expert guidance on state-of-the-art, multidisciplinary care for children and families. • Stay up to date with the most recent advances in the field with the contributions by new and returning contributors, including the perspective from patients and parents in the chapter titled “The Other Side of the Bed.” • Chapters included on palliative care and education. • Supportive care is covered broadly and specifically – in contexts such as emergencies, infectious disease, and nutrition. • Benefit from completely new and updated information throughout. • The most updated and authoritative information is provided by the leading experts in the field. • Gain a thorough understanding of every aspect of pediatric oncology, with comprehensive information regarding basic science, diagnostic tools, principles of treatment, and clinical trials, as well as highly detailed, definitive coverage of each pediatric malignancy. • Collaborate more effectively with others on the cancer care team to enhance quality-of-life issues for patients and families. • Understand the cooperative nature of pediatric oncology as a model for cancer research with information from cooperative clinical trial groups and consortia. Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: • Complete content with enhanced navigation • Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web • Cross-linked pages, references, and more for easy navigation • A highlighting tool for easier reference of key content throughout the text • Ability to take and share notes with friends and colleagues • Quick reference tabbing to save your favorite content for future use

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     Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more. This unique, continually updated reference remains the gold standard reference in the field with: A focus on immunotherapy throughout and new chapters on precision oncology and the microbiome. Guidance on managing every type of cancer, while incorporating recent treatment advances. The most effective strategies for managing every type of cancer by stage of presentation. Balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist. Important related topics such as cancer screening and prevention, palliative care, supportive oncology, and quality of life issues. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

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    The fifth edition of the only comprehensive text dealing exclusively with rare or infrequently encountered malignancies in adults and children is an essential resource for any clinical oncologist.

    ·                     Encompasses all the information needed to diagnose and manage uncommon cancers, an area where advice and guidance is typically scarce

    ·                     Fully revised with new material and an evidence-based, teach-by-example approach

    ·                     Provides insight on real-world decision making in the clinical setting

    ·                     Edited and authored by a highly experienced and senior team of medical oncologists, radiation oncologists, and other specialists, giving a balanced and complete overview

    ·                     Extensively illustrated in full color throughout, including heat maps to show gene expression

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