IBS affects almost one in six Americans and is characterized by abdominal pain, bloating, gas, and diarrhea and constipation. Today physicians are better able to diagnose this complex disorder, understand and explain its origins, and develop a treatment plan that effectively meets the individual needs of a patient. Since publication of the first edition of "Making Sense of IBS", diagnosis and treatment of irritable bowel syndrome have changed significantly. Drawing on his many years of experience treating people who have symptoms of IBS, Dr. Brian E. Lacy has greatly expanded the first edition, adding new topics and the latest findings on tests, medications, alternative treatments, dietary factors, and lifestyle. Dr. Lacy explains normal digestion, the causes of IBS, how IBS is diagnosed, and what to expect with treatment. He also explores special topics such as IBS in children and psychological, hypnotherapeutic, and psychiatric therapies. Important new information in the second edition includes: - the roles of fiber, gluten, lactose, and fructose in the development and treatment of IBS - the use of probiotics and antibiotics to treat IBS - similarities and differences between IBS and inflammatory bowel disease (IBD) - the relationship between small intestine bacterial overgrowth and IBS - how to make the most of your visits to a gastroenterologist - lifestyle modifications that can improve symptoms of IBS "Making Sense of IBS" is an essential resource for anyone who has symptoms or a diagnosis of IBS as well as for health professionals who treat people with this complex disorder.

Gain a complete understanding of the functioning of the gastrointestinal system with this concise, engagingly written text "Gastrointestinal Physiology" explains the operation and performance of one of the body's most crucial systems. Using clear, compelling language, the book's presentation makes it easy to absorb the content and integrate it as you learn the physiology of other bodily systems. Written to help you understand essential concepts rather than merely memorize facts, this unique text examines many medically relevant facets of this important body system, including anatomy, pathophysiology, and therapeutics, in concert with physiological information. FEATURES: Provides a thorough review of core concepts and highlights clinical application Covers the physiologic principles needed to understand and treat patients with digestive and liver diseases Includes clinical examples that link basic science with the practice of medicine Incorporates new information on emerging topics such as the communication between the intestine and central nervous system that controls food intake, the myriad roles newly ascribed to the intestinal microbiota, contemporary approaches to therapy for a number of GI maladies, and the role of the gut in obesity Enhanced by valuable learning aids such as study questions, learning objectives, key concepts, numerous illustrations and charts, and recommended readings

Fully revised and updated for the new edition, the Oxford Handbook of Gastroenterology and Hepatology comprises a unique A-Z compendium of the specialty, and a dedicated section detailing 30 of the most common problems in GI medicine, which can be used as a quick reference. A new section on clinical practice and diagnostics provides valuable new guidance on diagnostic procedures and reduces the time needed to search for each individual procedure and its associated complications. Further enhanced sections include emergencies, and commonly used drugs used in gastroenterology and hepatology, with emphasis on practice tips and common complications. Reflecting current approaches in training and curricula, the handbook has been arranged to reflect a clinical problems-based approach. Navigability has been enhanced, with a comprehensive index as well as an anatomical index being added to the existing A-Z format to ensure the right information will always be at your fingertips. The result of this new approach is a handbook which is practical, easy-to-use, and informative. It is an essential guide to the management of common conditions and is invaluable to all those involved in the care of patients with gastrointestinal disease.

This book is a practical guide to recent advances in the field of gastroenterology. This new edition has been fully revised and new topics added. Chapters cover the diagnosis and management of disorders in all areas of the gastrointestinal system. New to the second edition, are chapters on the latest modalities including nuclear medicine, positron emission tomography, and gastrointestinal manometry. Common geriatric and paediatric problems in gastroenterology have also been included in this edition.

Recent Advances in Gastroenterology: 13 is the ideal resource for keeping abreast of new developments within this fast moving field. Written by expert authors and featuring topics such as genetic-epidemiology of oesophageal cancer, polyposis syndromes and liver disease in pregnancy, each chapter introduces important principles that can be implemented into day to day treatment of GI disorders. Recent Advances in Gastroenterology: 13 is an invaluable revision tool for trainees, and a useful companion to practicing gastroenterologists wishing to stay current in all aspects of this field. *12 chapters summarising important recent advances within the field of gastroenterology * All topics are written in a practical and clinically relevant manner, further enhanced by the 'key clinical points for practice' sections at the end of each chapter * Provides an effective exam revision tool for gastroenterology portion of the MRCP(UK) and the SCE in Gastroenterology * All chapters written by expert authors ensuring authoritative and accurate content

Striking the perfect balance between comprehensiveness and ease of use, this popular entry in the CURRENT series delivers high-yield coverage of the entire spectrum of gastroenterology and hepatology in a streamlined, consistent presentation.

Gastroenterology as only Harrison's can covert it. Featuring a superb compilation of chapters related to gastroenterology that appear in Harrison's Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison's. You will find content from renowned editors and contributors in a carry anywhere presentation that is ideal for the classroom, clinic, war, or, exam/certification preparation. It features complete coverage of must-know gastroenterology and hepatology topics, including cardinal manifestations of disease, differential diagnosis and diagnostic evaluation, management of diseases and disorders, obesity, nutrition, and eating disorders. It reflects the most current advances in genetics, cell biology, pathophysiology, and treatment. Integration of pathophysiology with clinical management 107 high yield questions and answers drawn from Harrison's Principles of internal medicine; self Assessment and Board Review 18e 60 chapters written by physicians who are recognized experts in the field gatroenterology; and helpful appendix of laboratory values of clinical importance.

Gastroenterologists require detailed knowledge regarding the anatomy of the GI system in order to understand the disturbances caused by diseases they diagnose and treat. 

Gastrointestinal Anatomy and Physiology will bring together the world s leading names to present a comprehensive overview of the anatomical and physiological features of the gastrointestinal tract. 

Full colour and with excellent anatomical and clinical figures throughout, it will provide succinct, authoritative and didactic anatomic and physiologic information on all the key areas, including GI motility, hepatic structure, GI hormones, gastric secretion and absorption of nutrients. 

GI trainees will enjoy the self–assessment MCQs, written to the level they will encounter during their Board exams, and the seasoned gastroenterologist will value it as a handy reference book and refresher for re–certification exams

Mount Sinai Expert Guides: Gastroenterology will provide physicians with an extremely clinical and accessible handbook covering the major GI diseases and symptoms, their diagnosis and clinical management. Perfect as a point-of-care resource on the hospital wards and also as a refresher for board exam preparation, the focus throughout is on providing rapid reference, essential information on each disease to allow for quick, easy browsing and assimilation of the must-know information. All chapters follow a consistent template including the following features:

- An opening bottom-line/key points section
- Classification, pathogenesis and prevention of disease
- Evidence-based diagnosis, including relevant algorithms, laboratory and imaging tests, and potential pitfalls when diagnosing a patient
- Disease management including commonly used medications with dosages, when to perform surgery, management algorithms and how to prevent complications
- How to manage special populations, ie, in pregnancy, children and the elderly
- The very latest evidence-based results, major society guidelines (ASG/ACG/UEGW) and key external sources to consult In addition, the book comes with a companion website housing extra features such as case studies with related questions for self-assessment, key patient advice and ICD codes. Each guide also has its own mobile app available for purchase, allowing you rapid access to the key features wherever you may be. If you specialise in gastroenterology and require a concise, practical guide to the clinical management of GI disease, bought to you by one of world's leading hospitals, then this is the perfect book for you.

This atlas, featuring a wealth of high-quality images, offers a comprehensive overview of therapeutic gastrointestinal endoscopy for upper and lower gastrointestinal diseases. Both established and new therapeutic techniques using advanced endoscopic devices are extensively covered. The concise text accompanying the endoscopic photographs and illustrations will enable readers to understand the details of each procedure. Special tips of practical value are highlighted and potential pitfalls, identified. The authors are experts in the field who have a great store of knowledge on a wide variety of therapeutic endoscopic procedures. Gastrointestinal endoscopy is the principal tool for the investigation and treatment of most diseases of the gastrointestinal tract. This book will provide the clear guidance that practitioners require in order to perform therapeutic gastrointestinal endoscopy optimally; it will prove indispensable for all gastrointestinal endoscopists.

 Many bacteria, viruses, protozoa, and fungi play key roles in the development of gastrointestinal diseases, and this practical reference brings you up to speed with this increasingly important area. Covering a broad range of GI diseases and cancers, this resource provides an expert overview of the field, ideal for all gastroenterologists and infectious disease physicians.

Covers infections associated with gastroesophageal reflux disease and Barrett's esophagus, gallbladder disease, acute pancreatitis, small intestinal bacterial overgrowth, irritable bowel syndrome, inflammatory bowel disease, appendicitis, Whipple Disease, Crohn's Disease, and more.

Discusses esophageal cancer, gastric cancer, cholangiocarcinoma, hepatocellular carcinoma, and colorectal cancer.

Includes chapters on gut microbiome, fecal transplants, and the molecular pathgenesis of gastrointestinal infections.

Consolidates today's available information on this timely topic into a single convenient resource.

The new edition of this book provides a comprehensive review of the basic tests available in gastroenterology. Chapters examine widely-used modern techniques such as ultrasonography for Crohn’s disease, capsule endoscopy, elastography and video proctosigmoidoscopy among others. Fully updated to reflect the recent advances in the field in the last 20 years, this volume evaluates investigations for their current clinical usefulness in the management of patients. The reader will benefit from a critical analysis describing those older tests which have proved their worth alongside the newer procedures which have been introduced. Emphasis is placed on those techniques of which the authors have personal experience. The book is designed for trainees and clinicians without special expertise in gastroenterology, as well as being a shelf manual for the gastroenterologist and the staff of gastroenterology investigation units.

This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic and therapeutic procedures and future perspectives.

Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.

Provides clinicians with reliable, clearly presented information on current techniques in pathology, their uses and indications, and clinical–pathologic correlations

• Assist clinicians in their daily decision making by providing reliable, clearly presented information on current techniques in pathology
• Clinical correlations are presented with the aid of high-quality illustrations.

About this book

This is the first volume in a new Springer series, Pathology for Clinicians, which aims to assist clinicians in their daily decision making by providing reliable, clearly presented information on current techniques in pathology, their uses and indications, clinical–pathologic correlations, and the significance of pathologic diagnoses. Liver Pathology for Clinicians first discusses key technical aspects of liver biopsy, including the use of special stains and immunohistochemistry. Detailed guidance is provided on both common and uncommon indications for liver biopsy, including repeat or serial biopsies, and on the choice of procedure. The role of liver biopsy in the contexts of transplantation and systemic disease is also clearly explained. Clinical-pathologic correlations are presented with the aid of high-quality illustrations.

 

• Features a comprehensive overview of new therapies for patients with GERD
• Supplemented with color illustrations and tables
• Written by experts in the field

About this book

This volume presents the most recent developments in diagnosis and treatment of patients with gastroesophageal reflux disease (GERD) and those who continue to be refractory to conventional GERD therapies. The book delineates the role of newly developed endoscopic therapies in GERD and outlines the best candidates for surgical fundoplication. Topics as the risks associated with GERD, lifestyle modification in GERD and the role of H2RA and proton pump inhibitor therapy in treating reflux disease are also explored.

Written by authorities in the field, Diagnosis and Treatment of Gastroesophageal Reflux Disease is a concise yet comprehensive resource that is useful for primary care providers, gastroenterologists, pulmonologists, surgeons and ENT specialists.

 

Reviews

“This monograph focuses on the recent evidence-based literature about the many ways of diagnosing gastroesophageal reflux disease as well as the lifestyle modifications and medical, pharmacological, and surgical options for treatment. … This well researched, comprehensive monograph is a valuable read for every clinician treating patients with reflux disease and an absolute necessity for every academic library in a teaching facility.” (Vincent F. Carr, Doody’s Book Reviews, September, 2015)

 

Table of contents (8 chapters)

·         Definitions of Gastroesophageal Reflux Disease (GERD)

Patel, Amit (et al.)

Pages 1-17

·         Complications of Gastroesophageal Reflux Disease

Yachimski, Patrick

Pages 19-35

·         Diagnostic Approaches to GERD

Micic, Dejan (et al.)

Pages 37-57

·         Lifestyle Modifications in GERD

Akbar, Ali (et al.)

Pages 59-70

·         Role of H

Jacobs, John W. (et al.)

Pages 71-91

·         Novel Upcoming Therapies

Maradey-Romero, Carla (et al.)

Pages 93-115

·         Minimally Invasive GERD Therapies

Azagury, Dan E. (et al.)

Pages 117-143

·         Role of LES Augmentation for Early Progressive Disease in GERD and Fundoplication for End-Stage Disease in GERD

Worrell, Stephanie G. (et al.)

Inflammatory Bowel Diseases: A Clinician s Guide provides practical guidance for the diagnosis and management of those suspected or known to have one of the forms of these complex diseases. It is perfect both for gastroenterology trainees learning to care for these patients and the experienced physician as a concise and practical resource for day to day use.

Written by the experts, Inflammatory Bowel Diseases: A Clinician s Guide is an essential tool for all gastroenterologists managing patients with inflammatory bowel disease.

This book offers essential information on basic and translational research in gastric cancer, while also illustrating potential opportunities for its application in clinical practice. Gastric cancer is the fourth-most-common cancer globally and the second-leading cause of cancer deaths. It is known to be a heterogeneous disease with varied responses to “one-size-fits-all” treatments. Expanding our knowledge of cancer cell genetics may help us to explore more effective treatments in gastric cancer. The research on molecular mechanisms and its clinical applications, both presented here, will help readers gain an in-depth understanding of gastric cancer and its effective treatment.

The book’s four sections cover personalized medicine, precise regional therapy, immunotherapy and nanomedicine in gastric cancer. Each part presents the state of art, recent advances and the authors’ experiences. Moreover, several interesting cases are described to demonstrate how gastric cancer patients benefit from translational research. This informative and attractively presented book on precision treatment in gastric cancer, including experimental findings and clinical treatment options, offers a valuable resource for oncologists and graduate students working in the field of gastric cancer.

This volume serves as a reference for the dissemination of advances made in the study of Hepatitis B Virus (HBV). Hepatitis B Virus: Methods and Protocols details protocols and techniques ranging from cell culture studies to in vivo and clinical immunology. The chapters in this book discuss treatments of in vitro infection systems, analysis and quantification of cccDNA and its mutations; in vitro polymerase activity assays; cellular trafficking of core proteins; intracellular calcium metabolism; detection, cloning, and sequencing of HBV markers; and new strategies aimed at exploiting new mechanisms for drug discovery. The book also covers classical methods for resolution of extracellular viral particles by native gel electrophoresis, and methods for detecting HBV antigens in drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and comprehensive, Hepatitis B Virus: Methods and Protocols is a valuable tool for researchers to use toward their advanced studies in HBV.

This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects.

Hepatitis C Virus Treatment offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the characteristics of resistance, providing cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students.

This book examines the biological aspects of bile acid analysis and their clinical applications, providing readers with an overview of cutting-edge discussions on Bile Acid research and diseases. It begins with detailed discussions on the biological aspects of bile acid, with chapters examining bile acid from various perspectives, from its metabolism to its use in therapeutic agents. Subsequent chapters focus on diseases involving bile acid abnormalities, and specific applications are addressed concerning gallstones, cholestatic liver disease, NAFLD/NASH, hepatitis, pancreatitis, esophageal cancer and colon cancer. In keeping with the book’s integrated approach, the Editor has gathered a broad range of eminent scholars and practitioners to provide a comprehensive review of modern bile acid research. The book offers clinical physicians, basic researchers and postgraduate students essential insights into cutting-edge research and paves the way for further research.

Practical Endoscopy – Tips by Experts covers important surgeries related to laparoscopy and hysteroscopy in gynaecology and provides simple, practical tips to enhance surgical performance. This new edition is comprised of 43 chapters arranged in 5 sections; Basic Endoscopy, Hysteroscopy, Laparoscopy, Vaginal Surgery and Unusual Cases, with many new chapters and revision of old chapters.

The section on laparoscopy has been completely updated, with new chapters encompassing laparoscopic hysterectomy for multiple myomas, large fibroids, previous caesarean sections, endometriosis, intramural myoma, anatomy of pelvic floor and laparoscopic vault suspension, single incision laparoscopic surgery and robotic surgery in gynaecology.

Chapters on surgical principles for vaginal surgery, apical and posterior vaginal wall repair have been added to the vaginal surgery section and more cases have been included in the unusual cases section.

Practical Endoscopy – Tips by Experts provides practical tips and footnotes for each chapter, along with over 750 full colour images and illustrations. This comprehensive book, with contributions from experts in the field of obstetrics and gynaecology, is essential reading for postgraduate and practising endoscopists.

Key Features

• New edition features many new and fully revised chapters
• Completely updated laparoscopy section
• 750+ full colour images and illustrations

This book provides a comprehensive overview of Gastroesophageal reflux (GER) in children, discussing its epidemiology, pathophysiology diagnosis and treatments. Readers will discover diverse perspectives of the contributing authors and extensive discussions of issues including GER in special patient populations and current approaches to GER diagnosis and management.

The first part of the book is dedicated to introducing the condition, discussing epidemiology, symptoms and diagnosis. This is followed by addressing issues of the condition encountered in special patient populations such as in preterm infants, apnea, neulorogic patients and cystic fibrosis, among others. The final part of the book is dedicated to therapeutic approaches from meditation to surgery and alternative approaches such as complementary medicine and hypnotherapy. The approaches and challenges in endoscopy are discussed in a final chapter.

Edited by a leading world expert i

n the topic and written by a global team of authors, this book will appeal to a wide readership from pediatricians, gastroenterologists to pulmonologists, otolaryngologists and neurologists.For the first time, information on GER in patients 0--15 years is brought together in one volume, discussing all the key issues that for experts.

This book is a concise guide to the clinical diagnosis and management of chronic pancreatitis, presenting the latest research into the disease. It focuses on pathogenesis, epidemiology, genetics, diagnosis, endoscopic and surgical treatment, and prognosis. It also offers comprehensive descriptions of 4 diagnostic methods and discusses the contemporary management of chronic pancreatitis, including conservative, ESWL, interventional and surgical treatments. The final chapter includes 6 typical case presentations, which taken together provide a standard description of this condition.

New Approaches to Aortic Disease from Valve to Abdominal Bifurcation provides a complete look at aortic valve diseases from all points of view, including etiology, physiopathology, prevention, diagnosis and treatment. The book offers new insights into the aortic valve and pathology based on evidence of current diagnostic methods, treatments and post-surgery evolution. Content is split into three distinct parts for ease of reference, including an overview of aortic pathology, diagnostic evaluations methods, and treatments. Also included are guidelines and future research directions, making this a must-have volume for all cardiologists and cardiovascular surgeons who address significant issues in this topic area. Present pathophysiological sequences that are shown in correlation with histological details Includes detailed clinical examinations and the value of the initial assessment using chest X-ray, echocardiography, angiography, CT angiography and magnetic resonance, etc. Provides conventional descriptions of surgical techniques that are entirely detailed, along with long-term results and possible complications

 This book answers key questions asked by emergency clinicians faced with complex gastrointestinal and abdominal pain presentations. Instead of a traditional format that includes epidemiology, pathophysiology, diagnosis, and treatment options, this book takes an approach that mirrors the way clinicians interact with patients - by asking and answering specific clinical care questions. The book is organized into sections by presentation - gastrointestinal bleeding, for example - each of which contains chapters on specific questions, such as "What is the best clinical risk score for low risk GIB patients?" Each clinical question comes with a detailed, evidence-based response and a summary that gives best practices, recommendations, and references. Additionally, at the end of each section is a chapter titled "Expert Corner," which asks the same clinical questions to a surgical or gastrointestinal specialist and includes key pearls these experts have for emergency medicine practitioners. Gastrointestinal Emergencies: Evidence-Based Answers to Key Clinical Questions is an essential guide for emergency medicine physicians, residents, and medical students who want to review and improve their care of acute gastrointestinal emergencies.

• Presents the latest knowledge on all aspects of H. pylori infection and its consequences
• Offers detailed guidance on diagnosis and treatment
• Covers epidemiology, pathophysiology, antibiotic resistance, and reinfection rates

 

About this book

This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients.

The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.

• Covers new practices of surgical treatment of upper abdominal digestive diseases
• Introduces surgical procedures and systematizes all surgical steps
• Shares knowledge through illustrations and videos
• Supports teaching through discussion of different modalities of practical educational programs, including telementoring

About this book:

This book aims to comprehensibly describe the minimally invasive technique including robot assisted procedures of upper abdominal cancer, including aspects such as surgical anatomy, neoadjuvant therapy and minimally invasive surgical technique, and robot assisted procedures (5 alinea). Upper abdominal oncological surgery is increasingly approached by Minimally Invasive Surgery (MIS). Due to the rising experience of young surgeons with MIS, the optimal imaging obtained during the procedure and the possibility of decreasing the postoperative complications has led to an increase of quality of life without compromising the completeness of resection.

The book bases its approach on the information gathered by MIS observation and the step-by-step descriptions, by using illustrations and videos of surgical procedures for oncological resections of esophageal and gastric cancer, as well as for duodenum, pancreas, spleen and liver cancers.

Furthermore, this book will serve as a teaching guide, providing a present-day introduction to the increasingly sophisticated performance of surgery required by general and specialized surgical practitioners. The reader will have access to a practical book with relevant information that guides adequate treatment.

A new, fully updated edition of the world?s most famous book on liver diseases with updating of all areas and inclusion of new specific topics, by internationally renowned specialists This brand new edition of the classic book on hepatology provides a concise, clearly presented and well-structured review across the whole spectrum of hepatobiliary diseases by some of the world?s leading hepatologists and hepatobiliary specialists. Where many other hepatology textbooks provide detailed accounts of basic science and clinical management, Sherlock's Diseases of the Liver and Biliary System, 13th Edition takes a different approach. Concentrating on the clinical decisions to be taken and the relevant supporting data, it is written and edited to maintain Sheila Sherlock's unique approach, in particular the clarity and layout of the text, and the explanatory figures and tables. The book is thus concise, highly accessible, and generously illustrated with over 700 attractive color figures. There is a pithy approach to each disease based both on evidence and on the authors? experience, the hallmark of this book. Based on these elements, the 12th edition was awarded first prize in the 2012 British Medical Association Book Awards in the Internal Medicine category. Sherlock's Diseases of the Liver and Biliary System begins by introducing the anatomy and function of the liver to readers, continuing then with in-depth coverage of liver biopsy techniques and interpretation, and fibrogenesis and its assessment. There are then chapters on all aspects of liver and biliary disease including acute liver failure, cirrhosis, portal hypertension, hepatic encephalopathy, ascites, hepatitis B and C, alcohol and the liver, non-alcoholic fatty liver disease, drug related liver reactions, cholestatic, autoimmune and genetic liver diseases, benign and malignant tumours and not least liver transplantation. There are also chapters on the liver in pregnancy, in the neonate, infancy and childhood, in systemic diseases and in infections. This new edition also features four new individual chapters focusing on coagulation, non-invasive assessment of fibrosis and cirrhosis; vascular diseases of the liver and portal vein thrombosis, and nutrition in liver disease. Digital downloads of the figures from this edition are offered on a companion website. Internationally recognized and loved, world-renowned hepatology book, first published in 1955 takes a one-of-a-kind, clinical approach maintaining Sheila Sherlock's clarity and legacy of presentation. Full colour throughout with 700 illustrative figures. Wide faculty of international contributors Sherlock's Diseases of the Liver and Biliary System, 13th Edition is an ideal primer in hepatology for students and trainees in hepatology and gastroenterology, and a valuable resource for all specialist gastroenterologists and hepatologists, paediatricians, pathologists, radiologists, general physicians and specialist nurses.

High–resolution endoscopy and narrowband imaging have revolutionized the field.  Edited by a gastroenterologist with a reputation for delivering outstanding material, this new edition of an award–winning atlas provides you with an outstanding collection of images, videos and expert diagnostic guidance to enhance your decision making.

To accelerate your learning, Dr. Cohen offers more than 2000 endoscopic images, emphasizing conditions for which NBI is particularly useful such as finding dysplasia in Barrett s mucosa, and diagnosing adenomatous colon polyps and providing exceptional preparation for the future of endoscopy practice, with a broad new look at normal and abnormal findings throughout the GI tract.

The book is divided into three main parts:

The basics of NBI

Clinical applications of NBI

Atlas of 2000 color images, broken into sections on the pharynx and esophagus, stomach, small intestine, and colon, including correlating histopathology and multiple examples of key pathologies

The accompanying website features more than 80 video clips containing over 3 hours of annotated video, to give you a complete sense of how HRE and NBI work and look in real time, including during therapeutic procedures. All of the over 1000 new images appear in much brighter color, reflecting the advance in scope technology since the first edition.  New chapters have been added to present the data supporting increased use of NBI in optical diagnosis and in the context of therapeutic procedures.   For the first time, brilliant images of the bile duct and pancreas are included as the imaging revolution has expanded to reach these new locations. This spectacular new imaging modality promises to enhance endoscopic decision making in real time, facilitate therapeutic maneuvers, make tissue sampling more precise and make resection of mucosal neoplasia more complete.

Expertly guiding you through the latest advances, this book facilitates your mastery of the field, and provides an up–to–date reference for gastroenterologists and endoscopists to improve their practice.

 Digestive System Tumours is the first volume in the fifth edition of the WHO series on the classification of human tumors. This series (also known as the WHO Blue Books) is regarded as the gold standard for the diagnosis of tumors and comprises a unique synthesis of histopathological diagnosis with digital and molecular pathology. These authoritative and concise reference books provide indispensable international standards for anyone involved in the care of patients with cancer or in cancer research, underpinning individual patient treatment as well as research into all aspects of cancer causation, prevention, therapy, and education.

What is new in this edition?
The fifth edition, guided by the WHO Classification of Tumours Editorial Board, will establish a single coherent cancer classification presented across a collection of individual volumes organized on the basis of anatomical site (digestive system, breast, soft tissue and bone, etc.) and structured in a systematic manner, with each tumor type listed within a taxonomic classification: site, category, family (class), type, and subtype. In each volume, the entities are now listed from benign to malignant and are described under an updated set of headings, including histopathology, diagnostic molecular pathology, staging, and easy-to-read essential and desirable diagnostic criteria.

Who should read this book?
- Pathologists
- Oncologists
- Gastroenterologists
- Cancer researchers
- Epidemiologists
- Cancer registrars

This volume: 
- Prepared by 168 authors and editors
- Contributors from 22 countries
- More than 1000 high-quality images
- More than 3700 references

Consult the leading text in the field that delivers the information you need to diagnose and treat pediatric gastrointestinal and liver diseases effectively. In one convenient and comprehensive volume, Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay provide all the latest details on the most effective new therapies, new drugs, and new techniques in the specialty. In addition, the new two-color design throughout helps you find what you need quickly and easily.

- Full-color endoscopy images to help improve your visual recognition.
- Definitive guidance from renowned international contributors who share their knowledge and expertise in this complex field.
- Detailed diagrams that accurately illustrate complex concepts and provide at-a-glance recognition of disease processes.
- More than 400 board review-style questions, answers, and rationales available in the eBook included with your purchase New therapies for hepatitis B and C, new drugs for the treatment of inflammatory bowel disease, and an expanded discussion of the newest endoscopic and motility techniques available for pediatric patients.
- The most current information on diagnosing and treating abnormalities of protein, fat, and carbohydrate metabolism New chapters on pancreatic transplantation and liver pathology.
-The latest surgical techniques for children with gastrointestinal conditions.

The fifth edition of Yamada's Atlas of Gastroenterology sees the return of the gold-standard multi-media atlas that provides gastroenterologists with an outstanding visual tool covering all facets of the field. Every GI disorder from liver abscesses, endocrine neoplasms of the pancreas, to motility disorders of the esophagus are fully illustrated through the use of endoscopic ultrasonographs, computed tomography scans, magnetic resonance images, radionuclide images, and angiograms.

Signalling Pathways in Liver Diseases 3E again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signalling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohatitis, cirrhosis and liver tumours, which has led in changes to the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as:
• Autophagy
• Notch Pathway
• PI3K/PTEN Signaling in Liver Diseases
• Sirtuins
• Hepcidin and Iron
• Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis
• Oxidative Stress and Signaling in the Liver Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom will provide write a clear yet comprehensive review of their chosen topic. Chapters will contain clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signalling Pathways in Liver Diseases 3E is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

 Part of the highly respected Master Techniques in Surgery series, Colon and Rectal Surgery: Abdominal Operations, 2nd Edition provides the authoritative, up-to-date guidance you need to master both traditional techniques and innovative new procedures in colon and rectal surgery. Covering both basic and advanced procedures, this edition contains superbly illustrated, expertly written chapters covering virtually any colorectal surgical technique likely to be performed today. Each contributing author presents a real-world viewpoint on a particular surgery, and outstanding full-color illustrations provide visual support for every procedure.

•             Presents easy-to-digest, clinically relevant material from world-renowned colon and rectal surgeons who explain their preferred techniques step by step, including indications and contraindications, preoperative planning, postoperative management, outcomes, complications, and follow-up.

•             Covers left and right colon resections performed open and laparoscopically, colectomies, proctocolectomies, abdominoperianal resections, restorative and reconstructive techniques for proctocolectomy and pelvis reconstruction, stomal complications, treatment of rectal prolapse, ventral hernia repair, and small bowel strictureplasty.

•             Includes 14 all-new chapters:

o             Transanal Total Mesorectal Excision

o             Robotic Total Colectomy with Ileorectal Anastomosis

o             Robotic Total Proctocolectomy

o             Robotic Restorative Proctocolecotmy

o             Robotic Abdominoperineal Resection

o             Extended Extralevator Abdominoperineal Resection

o             Ileal Conduit Construction After Exenteration (Bricker Conduit)

o             Posterior Sacrectomy and Reconstruction with Alloderm

o             Open Resection Rectopexy

o             Robotic Rectopexy

o             Laparoscopic Ventral Mesh Rectopexy

o             Parastomal Hernia: Laparoscopic Ventral Repair

o             Robotic Ventral Hernia Repair

o             Ventral Hernia: Component Separation Technique

Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities!Read directly on your preferred device(s), such as computer, tablet, or smartphone

•             Easily convert to audiobook, powering your content with natural language text-to-speech

•             Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more

Esophageal anomalies and disorders in infancy and childhood include a wide spectrum of different diseases. These range from emergencies immediately after birth such as esophageal atresia (EA), necessitating an experienced team of neonatologists and pediatric surgeons, up to gastro-esophageal reflux disease in elder children, necessitating the pediatric gastroenterologist and visceral surgeon. In the last few years some fascinating pediatric surgical techniques have evolved, such as the thoracoscopic correction of EA or the FOKER technique for elongation in cases of long-gap, EA. Prof. Foker has developed this special traction technique and is the world's leading expert in long-gap EA.

Now thoroughly up-to-date both in print and online, Clinical Gastrointestinal Endoscopy, 3rd Edition, by Drs. Vinay Chandrasekhara, Mouen Khashab, B. Joseph Elmunzer, and V. Raman Muthusamy, ensures that you stay current with the latest technology and techniques in GI endoscopy. An all-new editorial team, newly updated videos and images, and a reorganized format make this reference an easy-to-use source of reliable information on a full range of topics, including anatomy, pathophysiology, and therapeutic management options, in addition to the latest GI procedures and technologies. Features: ? Offers state-of-the-art coverage of bariatric surgery, therapeutic EUS, device-assisted enteroscopy, image-guided therapy, intramural endotherapy, and much more. New To This Edition: ? Features 100 updated videos with author voiceovers, as well as 1,000 revised photographs, endoscopic images, and anatomical drawings. ? Provides a fresh perspective and expert guidance from an entirely new editorial team. ? Includes many more references per chapter, as well as further references online. ? Presents material in a newly restructured, organ-based format for quick reference. ? Expert Consult? eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

For more than 55 years, "Schiff" has been acclaimed as the most outstanding liver book in the world. This new 12th edition brings the field completely up to date and includes a companion website that features a wide–variety of accessory materials. The text is evidence–based to offer hepatologists and gastroenterologists treating patients with liver disease a comprehensive and essential resource. The text highlights clinical practice and covers anatomy, pathology, testing, imaging, and the effects of liver disease on other organs.

The book is written in clear and accessible terms and key features include: Treatment guidelines and management algorithms for every disease Full–color attractive design throughout the text Informative section overviews for each section Concise key concepts box in every chapter A full liver transplant section This 12th edition is thoroughly revised with the latest clinical information. The new edition offers: Information on acute and chronic liver failure and infections in cirrhosis Over 100 MCQs Downloads for Powerpoint™ making the content ideal for presentations Schiff′s Diseases of the Liver is designed to be a first–stop reference for dealing with today’s demanding clinical situations.
Table of Contents
Contributors Foreword Preface
About the Companion
Website
Part I Overview: Clinical Fundamentals of Hepatology
1 History Taking and Physical Examination for the Patient with Liver Disease Esperance A. Schaefer and Lawrence S. Friedman
2 Laboratory Tests, Noninvasive Markers of Fibrosis, Liver Biopsy, and Laparoscopy Michael P. Curry and Lennox J. Jeffers
3 Noninvasive and Invasive Imaging of the Liver and Biliary Tract Koushik K. Das, Matthew A.Morgan, and Gregory G. Ginsberg Part II General Considerations
4 Physioanatomic Considerations Ian R. Wanless
5 Bilirubin Metabolism and Jaundice Allan W. Wolkoff and Paul D. Berk
6 Hepatic Histopathology Zachary D. Goodman
7 Mechanisms of Liver Injury Harmeet Malhi and Gregory J. Gores
8 Hepatic Manifestations of Systemic Disorders Stuart C. Gordon and Humberto C. Gonzalez
9 The Liver in Pregnancy Nancy Reau and Yannick Bacq Part III Consequences of Liver Disease
10 Hepatic Fibrosis Scott L. Friedman
11 Preoperative Evaluation of the Patient with Liver Disease Patrick S. Kamath and Mark T. Keegan
12 Management of Portal Hypertension Guadalupe Garcia-Tsao and Juan G. Abraldes
13 Renal Complications of Liver Disease and the Hepatorenal Syndrome, 33 Xingxing S. Cheng and W. Ray Kim
14 Pulmonary Manifestations of Liver Disease Michael B. Fallon and Anil Seetharam
15 Ascites and Spontaneous Bacterial Peritonitis Vicente Arroyo and Javier Fern´andez
16 Hepatic Encephalopathy Chathur Acharya and Jasmohan S. Bajaj
17 Acute Liver Failure Robert J. Fontana and Khurram Bari
18 Acute-on-Chronic Liver Failure Florence Wong
19 Malnutrition and Liver Disease Craig McClain, Irina Kirpich, and Laura Smart Part IV Cholestatic Disorders
20 Primary Sclerosing Cholangitis John M. Vierling
21 Primary Biliary Cholangitis Cynthia Levy, Andres F. Carrion, and Marlyn J. Mayo
22 Autoimmune Hepatitis Gideon M. Hirschfield and Gwilym J. Webb Part V Viral Hepatitis
23 Hepatitis A and E Kenneth E. Sherman and Shyam Kottilil
24 Hepatitis B and D Marc G. Ghany and Naveen Gara
25 Hepatitis C Michael W. Fried, Jama M. Darling, and Stanley M. Lemon Part VI Alcohol- and Drug-induced Liver Disease
26 Alcoholic Liver Disease Mack C. Mitchell and Gyongyi Szabo
27 Drug-induced Hepatotoxicity, 740 Dominique Larrey, Jose Ursic-Bedoya, and Lucy Meunier
28 Mechanisms of Drug-induced Liver Injury Paul B. Watkins and Merrie Mosedale Part VII Genetic and Metabolic Disease
29 Wilson Disease Michael L. Schilsky and Aftab Ala
30 Hemochromatosis and Iron Storage Disorders Kris V. Kowdley and Priya Handa
31 Alpha-1 Antitrypsin Deficiency David H. Perlmutter
32 Nonalcoholic Fatty Liver Disease Curtis K. Argo, Zachary H. Henry, and Stephen H. Caldwell Part VIII Vascular Diseases of the Liver
33 Vascular Liver Disease Dominique-Charles Valla
34 The Liver in Circulatory Failure Santiago J. Munoz, Hanisha R. Manickavasagan, and Idean Amirjazil Part IX Benign and Malignant Tumors; Cystic Disorders
35 Benign Tumors, Nodules, and Cystic Diseases of the Liver Julien Calderaro and Jessica Zucman-Rossi
36 Hepatocellular Carcinoma Maddie Kubiliun and Jorge A. Marrero
37 Surgical Options in Liver Cancers Garrett R. Roll and John Paul Roberts Part X Infectious and Granulomatous Disease
38 Amoebic and Pyogenic Liver Abscesses Marco A. Olivera-Mart´ýnez and David Kershenobich
39 Parasitic Diseases Michael A. Dunn
40 Granulomas of the Liver James H. Lewis Part XI Elements of Liver Transplantation
41 Selection of Candidates and Timing of Liver Transplantation Meaghan Phipps, Alyson N. Fox, and Robert S. Brown Jr.
42 Immunosuppression: The Global Picture Caroline C. Jadlowiec, Timucin Taner, and Russell H. Wiesner
43 The First Six Months Following Liver Transplantation K. Rajender Reddy and Manuel Mendizabal
44 Long-term Management of the Liver Transplant Patient Timothy M. McCashland
45 The Liver Transplant Procedure Bijan Eghtesad, Koji Hashimoto, and John Fung
46 Recurrent Disease Following Liver Transplantation Haripriya Maddur and Josh Levitsky
47 The Role of Retransplantation Peter L. Abt and Kim M. Olthoff
48 Controversies in Liver Transplantation James F. Trotter Index

Now in its 10th edition, Sleisenger and Fordtran’s Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments—with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos.

 The definitive full-color illustrated guide to abdominal operations for general, colorectal, and gastrointestinal surgeons

With each edition, Maingot's Abdominal Operations has built a legacy of expertise, currency, and clinical rigor acclaimed by surgical trainees and practicing surgeons. Presented in full-color, the Thirteenth Edition offers a concise, yet complete, survey of the diagnosis and management of benign and malignant digestive diseases. This authoritative resource has everything clinicians need to understand congenital, acquired, and neoplastic disorders--and optimize surgical outcomes for any type of abdominal procedure.

• Increased number of algorithms to assist surgical decision making

• Contemporary focus on operative procedures, and new concepts in the diagnosis and management of abdominal disease

• Convenient organ/procedure presentation provides a seamless review of surgical protocols, as well as pre- and postoperative strategies and techniques

• “Perspective Chapters” provide insight from thought leaders on the latest developments in abdominal surgery

• Chapters on gastrointestinal bleeding, abdominal trauma, and abdominal vascular emergencies--along with minimally invasive surgery chapters woven throughout the text--present current, ready-to-use insights designed to enhance surgical care and recovery

• More than 1,250 illustrations (most in full color)

1246 RON 1100 RON

Description:
Ideal for trainees and practicing radiologists, Diagnostic Imaging: Gastrointestinal, 3rd Edition provides comprehensive coverage of every important topic in abdominal and gastrointestinal imaging. Featuring an increased number of illustrations, graphics, and multimodality imaging, this updated medical reference book will aid you in recognizing the characteristic and variant appearances of both common and uncommon abdominal disorders. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need!
Features:
• Expanded coverage of the most important topics and trends in fluoroscopic evaluation of the GI tract, including evaluation of patients before and after bariatric surgery, fundoplication, and surgery for esophageal carcinoma.
• Updated sections covering disorders of the liver, biliary tract, and pancreas with information and images regarding new classification and treatment implications for pancreatitis, including autoimmune (IgG4-related) pancreatitis.
• Increased number of illustrations of all appropriate imaging modalities, such as multiplanar CT, sonography, MR, and PET/CT.
• Offers information on all forms of acute and chronic hepatitis and cirrhosis, as well as critical knowledge regarding imaging techniques that allow radiologists to distinguish among focal lesions in the cirrhotic liver.
• Essential information is distilled into a succinct, bulleted format with numerous high-quality images and "Key Facts" boxes to facilitate learning.
• Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.

Praise for the previous edition:

"Extraordinary achievement … this volume stands on its own as a marvelous feat in bringing such a vast array of clear and coherent instruction to endoscopists at all skill levels."—Gastroenterology

Written and edited by internationally renowned specialists, the third edition of Gastroenterological Endoscopy covers the entire spectrum of diagnostic and therapeutic procedures for the upper and lower GI tract while providing the latest overview of GI disorders. A great wealth of high-resolution photographs provides the visual information needed to confidently assess and diagnose mucosal lesions of the entire digestive tract. Significant advances in the field—both medical and technical—since the last edition are covered in comprehensive detail.

Key Features:

·         New panel of top international editors, continuing the tradition of excellence, depth, and breadth as originated by founding editors Classen, Tytgat, and Lightdale; list of contributing authors is a "who's who" of GI endoscopy

·         Coverage of newest, advanced tools and techniques: gastric-POEMS, submucosal tunnel endoscopic resection (STER), lumen-apposing metal stents, "over-the-scope" clips, and much more

·         More than 1,500 exquisite images

Gastroenterological Endoscopy, third edition, surely deserves a prominent place in any complete endoscopy reference collection.

Michael B. Wallace, MD, is Professor of Medicine at the Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA

Paul Fockens, MD, is Professor and Chair of the Dept. of Gastroenterology and Hepatology at the Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Joseph Jao-Yiu Sung, MD, PhD, is Mok Hing Yiu Professor of Medicine and Director of the Institute of Digestive Diseases of The Chinese University of Hong Kong, Shatin, Hong Kong

An award-winning international medical and scientific publisher, Thieme has demonstrated its commitment to the highest standard of quality in the state-of-the-art content and presentation of all its products. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in online and print publishing.

The revised fourth edition of Evidence-Based Gastroenterology and Hepatology continues to provide the most current, evidence-based information for determining the appropriate medical and surgical options for screening for, diagnosing, and treating gastrointestinal conditions. With contributions from an international team of leading experts in the field, the 4th edition includes practical recommendations for the care of individual patients based on the latest scientific evidence.

For more than 60 years, Shackelford’s Surgery of the Alimentary Tract has served as the cornerstone reference in this fast-moving field. With comprehensive coverage of all aspects of GI surgery, the 8th Edition, by Drs. Charles J. Yeo, Steven R. DeMeester, David W. McFadden, Jeffrey B. Matthews, and James W. Fleshman, offers lavishly illustrated, authoritative guidance on endoscopic, robotic, and minimally invasive procedures, as well as current medical therapies. Each section is edited by a premier authority in GI surgery; chapters reflect key topics and are written by a "who’s who" of international experts in the field. It’s your one-stop resource for proven, systematic approaches to all relevant adult and pediatric GI disorders and operations

Features:
•    Features an abundance of beautifully detailed intraoperative and laparoscopic photographs, as well as radiographs and line drawings, to enhance and clarify the text.
•    Presents essential information, such as lists of differential diagnoses, in tabular format for quick reference.

New To This Edition:
•    Discusses recent, major advances in minimally invasive surgery and robotic surgery, personalized therapy based on genomics and proteomics, and new pharmacologic treatments of various GI diseases.
•    Includes all-new information on laparoscopy for rectal cancer, sacral nerve stimulation for incontinence and constipation, management of Crohn’s disease and ulcerative colitis, advances in immunosuppression for transplant patients, and new therapies for inflammatory bowel disease.
•    Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Yamada s Textbook of Gastroenterology has for 20 years been the most comprehensive gastroenterology reference book, combining an encyclopaedic basic science approach to GI and liver disease with the latest clinical thinking, especially in diagnostic and therapeutic developments. It is universally respected across the globe. It has always had an outstanding editor team led by Tachi Yamada, one of the world s leading figures in GI research, and in addition, a hugely impressive team of contributors, each experts in their specific area. Now with a new Editor–in–Chief, Dan Podolsky, Professor of Internal Medicine at the University of Texas Southwestern Medical Center, the 6th edition of this iconic textbook is modernising and improving in a number of ways: Now with free, fully searchable access to the entire digital text with every print purchase. A templated chapter approach, including separate chapter templates for a) basic science chapters; b) disease chapters and c) symptom chapters, resulting in more consistency in both structure, content and length of chapters. Far more clinically focused than before by virtue of a brand new section "Principles of Clinical Gastroenterology". Containing 14 symptom–focused chapters, it will enable doctors to assess their patients in the clinic more effectively than ever. Increased coverage of key topics like autoimmune pancreatitis, fecal biomarkers, genetics, IBD, IgG4 systemic disease , Crohn s disease, ulcerative colitis, and eosinophilic esophagitis. Downloadable hot topic podcasts from the world s key GI experts. Greater emphasis on clinical studies/trials, evidence–based practice, society guidelines, and governmental agencies than before. Every reference online, with hyperlinks to Pubmed/CrossRef, rather than ′static′ print references. Key references will be retained in print. For more international and global authorship – along with the leading North American figures, the top European and Asian GI experts provide their expertise and insights throughout. Yamada s Textbook of Gastroenterology 6E is the complete gastroenterology reference book. With a greater than ever clinical focus, not only does it retain its position as the market leader in terms of basic science coverage, but it also cements itself as an outstanding resource to consult in terms of the clinical management of GI disorders. Better than ever and with free, fully searchable access to the entire content digitally with the print book, it suits the needs of the modern day gastroenterologist, whether experienced or at the beginning of their career.