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Diagnostic Pathology: Soft Tissue Tumors

by Matthew R. Lindberg

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Cod produs/ISBN: 9780443109362

Disponibilitate: La comanda in aproximativ 4 saptamani

Autor: Matthew R. Lindberg

Editura: Elsevier

Limba: Engleza

Nr. pagini: 920

Coperta: Hardcover

Dimensiuni:

An aparitie: 15 Aug 2023

Descriere
Comentarii / Reviews

Description: This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering the wide range of often difficult-to-diagnose variants and subtypes in soft tissue tumors, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the fourth edition of Diagnostic Pathology: Soft Tissue Tumors is a visually stunning, one-stop resource for every practicing pathologist, oncologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.
Features:
Provides up-to-date, comprehensive coverage of soft tissue pathology combined with accurate, concise clinicopathologic descriptions, helping you quickly identify tumors and establish actionable diagnoses Contains hundreds of chapters with separate Benign, Intermediate, and Malignant sections to provide the fullest diagnostic picture possible Features new chapters covering the recently recognized EWSR1::SMAD3 fibroblastic tumor, plexiform myofibroblastoma, anastomosing hemangioma, myxoid pleomorphic liposarcoma, and more Includes details throughout on new immunostains and molecular genetics and testing Features an image-rich layout with more than 4,400 print and online-only images—including high-quality photomicrographs, gross photographs, radiologic images, and detailed medical illustrations—to make tumor identification and diagnosis faster and easier Provides an organized framework that includes "Approach to Diagnosis" chapters designed to help you successfully recognize and diagnose challenging soft tissue tumors with the availability of common patterns and histologic features Includes updates based on the most recent WHO Classification of Tumors: Soft Tissue and Bone Tumors Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care Includes an digital version that enables you to access all text, figures, and references with the ability to search, customize your content, make notes and highlights, and have content read aloud
Table Of Contents:
SECTION 1: SOFT TISSUE INTRODUCTION INTRODUCTION AND OVERVIEW 4 Gross Examination Matthew R. Lindberg, MD 6 Grading and Staging Matthew R. Lindberg, MD ANCILLARY TECHNIQUES 12 Soft Tissue Immunohistochemistry Matthew R. Lindberg, MD 18 Molecular Features of Soft Tissue Tumors Matthew R. Lindberg, MD SECTION 2: DIAGNOSTIC APPROACH TO SOFT TISSUE TUMORS OVERVIEW 22 Biopsy and Resection of Soft Tissue Tumors Matthew R. Lindberg, MD CLINICAL APPROACH 26 Age- and Location-Based Approach to Diagnosis Matthew R. Lindberg, MD HISTOLOGIC APPROACH 28 Pattern-Based Approach to Diagnosis Matthew R. Lindberg, MD 36 Feature-Based Approach to Diagnosis Matthew R. Lindberg, MD SECTION 3: TUMORS OF ADIPOSE TISSUE BENIGN 46 Lipoma Matthew R. Lindberg, MD 52 Lipomatosis of Nerve Michella Whisman, MD and Jerad M. Gardner, MD 54 Synovial Lipomatosis Matthew R. Lindberg, MD 56 Angiolipoma Michella Whisman, MD and Jerad M. Gardner, MD 60 Spindle Cell/Pleomorphic Lipoma Matthew R. Lindberg, MD 66 Chondroid Lipoma Matthew R. Lindberg, MD 70 Myolipoma Michella Whisman, MD and Jerad M. Gardner, MD 74 Hibernoma Matthew R. Lindberg, MD 78 Myelolipoma Matthew R. Lindberg, MD 80 Lipoblastoma Matthew R. Lindberg, MD 84 Atypical Spindle Cell/Pleomorphic Lipomatous Tumor Matthew R. Lindberg, MD 88 Lipoblastoma-Like Tumor of Vulva Matthew R. Lindberg, MD INTERMEDIATE, LOCALLY AGGRESSIVE 92 Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Matthew R. Lindberg, MD MALIGNANT 98 Dedifferentiated Liposarcoma Matthew R. Lindberg, MD 106 Myxoid Liposarcoma Matthew R. Lindberg, MD 112 Pleomorphic Liposarcoma Matthew R. Lindberg, MD 118 Myxoid Pleomorphic Liposarcoma Matthew R. Lindberg, MD SECTION 4: FIBROBLASTIC/MYOFIBROBLASTIC LESIONS BENIGN 124 Nodular Fasciitis Matthew R. Lindberg, MD 130 Proliferative Fasciitis/Myositis Matthew R. Lindberg, MD 134 Ischemic Fasciitis Matthew R. Lindberg, MD 136 Myositis Ossificans Matthew R. Lindberg, MD 140 Fibroosseous Pseudotumor of Digits David Lucas, MD and Elizabeth A. Montgomery, MD 144 Fibroma of Tendon Sheath David Lucas, MD 150 Desmoplastic Fibroblastoma David Cassarino, MD, PhD and Khin Thway, MD, FRCPath 152 Elastofibroma Matthew R. Lindberg, MD 154 Angiofibroma of Soft Tissue Matthew R. Lindberg, MD 158 Mammary-Type Myofibroblastoma Matthew R. Lindberg, MD 162 Plexiform Myofibroblastoma Matthew R. Lindberg, MD 166 Intranodal Palisaded Myofibroblastoma Matthew R. Lindberg, MD 170 Pleomorphic Fibroma David Cassarino, MD, PhD 172 Dermatomyofibroma David Cassarino, MD, PhD 174 Fibroblastic Connective Tissue Nevus Matthew R. Lindberg, MD 176 Storiform Collagenoma David Cassarino, MD, PhD 178 Keloid David Cassarino, MD, PhD 180 Nuchal-Type Fibroma Matthew R. Lindberg, MD INTERMEDIATE (LOCALLY AGGRESSIVE) 182 Palmar/Plantar Fibromatosis Matthew R. Lindberg, MD 184 Desmoid-Type Fibromatosis Matthew R. Lindberg, MD *190 EWSR1::SMAD3* Fibroblastic Tumor** Matthew R. Lindberg, MD INTERMEDIATE (RARELY METASTASIZING) 194 Dermatofibrosarcoma Protuberans Matthew R. Lindberg, MD 204 Solitary Fibrous Tumor Matthew R. Lindberg, MD 212 Low-Grade Myofibroblastic Sarcoma Matthew R. Lindberg, MD 216 Inflammatory Myofibroblastic Tumor Matthew R. Lindberg, MD 222 Myxoinflammatory Fibroblastic Sarcoma Matthew R. Lindberg, MD 230 Superficial CD34(+) Fibroblastic Tumor Matthew R. Lindberg, MD MALIGNANT 234 Adult-Type Fibrosarcoma Michella Whisman, MD and Jerad M. Gardner, MD 236 Myxofibrosarcoma Matthew R. Lindberg, MD 242 Low-Grade Fibromyxoid Sarcoma Matthew R. Lindberg, MD 252 Sclerosing Epithelioid Fibrosarcoma Matthew R. Lindberg, MD 258 Epithelioid Inflammatory Myofibroblastic Sarcoma Matthew R. Lindberg, MD SECTION 5: PEDIATRIC FIBROBLASTIC/MYOFIBROBLASTIC TUMORS BENIGN 264 Fibrous Hamartoma of Infancy Matthew R. Lindberg, MD 268 Calcifying Aponeurotic Fibroma Matthew R. Lindberg, MD 272 Calcifying Fibrous Tumor Michella Whisman, MD, Kandi Stallings-Archer, MD, and Elizabeth A. Montgomery, MD 274 Inclusion Body Fibromatosis Matthew R. Lindberg, MD 276 Hyaline Fibromatosis Syndrome Michella Whisman, MD, Elizabeth A. Montgomery, MD, and Cyril Fisher, MD, DSc, FRCPath 278 Fibromatosis Colli Michella Whisman, MD, Kandi Stallings-Archer, MD, and Cyril Fisher, MD, DSc, FRCPath 280 Gardner Fibroma Michella Whisman, MD and Jerad M. Gardner, MD INTERMEDIATE (LOCALLY AGGRESSIVE) 282 Lipofibromatosis Michella Whisman, MD, Kandi Stallings-Archer, MD, and Elizabeth A. Montgomery, MD 284 Giant Cell Fibroblastoma Matthew R. Lindberg, MD INTERMEDIATE (RARELY METASTASIZING) 288 Infantile Fibrosarcoma Matthew R. Lindberg, MD SECTION 6: FIBROHISTIOCYTIC, HISTIOCYTIC, AND DENDRITIC CELL TUMORS BENIGN 294 Dermatofibroma and Fibrous Histiocytoma David Cassarino, MD, PhD 300 Deep Benign Fibrous Histiocytoma Matthew R. Lindberg, MD 302 Epithelioid Fibrous Histiocytoma David Cassarino, MD, PhD 306 Localized-Type Tenosynovial Giant Cell Tumor David Lucas, MD 312 Diffuse-Type Tenosynovial Giant Cell Tumor David Lucas, MD 318 Cellular Neurothekeoma Michella Whisman, MD, Jerad M. Gardner, MD, and Cyril Fisher, MD, DSc, FRCPath 322 Xanthomas Matthew R. Lindberg, MD 326 Solitary (Juvenile) Xanthogranuloma David Cassarino, MD, PhD and Elizabeth A. Montgomery, MD 328 Reticulohistiocytoma David Cassarino, MD, PhD 332 Deep Granuloma Annulare Nicholas Zoumberos, MD and Jerad M. Gardner, MD 334 Rheumatoid Nodule Nicholas Zoumberos, MD and Jerad M. Gardner, MD 336 Langerhans Cell Histiocytosis Matthew R. Lindberg, MD 338 Extranodal Rosai-Dorfman Disease Matthew R. Lindberg, MD 342 Crystal-Storing Histiocytosis Matthew R. Lindberg, MD and Elizabeth A. Montgomery, MD INTERMEDIATE (RARELY METASTASIZING) 344 Plexiform Fibrohistiocytic Tumor Matthew R. Lindberg, MD 348 Giant Cell Tumor of Soft Tissue David Lucas, MD MALIGNANT 352 Histiocytic Sarcoma Matthew R. Lindberg, MD 354 Follicular Dendritic Cell Sarcoma Matthew R. Lindberg, MD 358 Interdigitating Dendritic Cell Sarcoma Matthew R. Lindberg, MD, L. Jeffrey Medeiros, MD, and Cyril Fisher, MD, DSc, FRCPath SECTION 7: SMOOTH MUSCLE TUMORS BENIGN 362 Smooth Muscle Hamartoma Nicholas Zoumberos, MD and Jerad M. Gardner, MD 364 Superficial Leiomyoma Nicholas Zoumberos, MD, Jerad M. Gardner, MD, and Jonathan B. McHugh, MD 368 Deep Leiomyoma Matthew R. Lindberg, MD INTERMEDIATE 372 Epstein-Barr Virus-Associated Smooth Muscle Tumor David Lucas, MD MALIGNANT 374 Leiomyosarcoma Matthew R. Lindberg, MD SECTION 8: PERICYTIC (PERIVASCULAR) TUMORS BENIGN 382 Glomus Tumors (and Variants) Thomas Mentzel, MD and Matthew R. Lindberg, MD 388 Myopericytoma Matthew R. Lindberg, MD and Thomas Mentzel, MD 392 Myofibroma and Myofibromatosis Matthew R. Lindberg, MD 396 Angioleiomyoma Matthew R. Lindberg, MD SECTION 9: TUMORS OF SKELETAL MUSCLE BENIGN 400 Focal Myositis Matthew R. Lindberg, MD and Cyril Fisher, MD, DSc, FRCPath 402 Adult Rhabdomyoma Matthew R. Lindberg, MD 404 Fetal Rhabdomyoma Matthew R. Lindberg, MD 406 Genital Rhabdomyoma Matthew R. Lindberg, MD 408 Cardiac Rhabdomyoma Matthew R. Lindberg, MD MALIGNANT 410 Embryonal Rhabdomyosarcoma Matthew R. Lindberg, MD 416 Alveolar Rhabdomyosarcoma Matthew R. Lindberg, MD 422 Spindle Cell/Sclerosing Rhabdomyosarcoma Matthew R. Lindberg, MD 426 Pleomorphic Rhabdomyosarcoma Michella Whisman, MD and Jerad M. Gardner, MD 430 Epithelioid Rhabdomyosarcoma Matthew R. Lindberg, MD SECTION 10: VASCULAR TUMORS (INCLUDING LYMPHATICS) BENIGN 434 Papillary Endothelial Hyperplasia David Cassarino, MD, PhD and Amitabh Srivastava, MD 436 Bacillary Angiomatosis David Cassarino, MD, PhD 438 Cutaneous Epithelioid Angiomatous Nodule Matthew R. Lindberg, MD 440 Congenital Hemangioma Michella Whisman, MD and Kandi Stallings-Archer, MD 444 Infantile Hemangioma Michella Whisman, MD and Kandi Stallings-Archer, MD 448 Lobular Capillary Hemangioma Matthew R. Lindberg, MD 450 Epithelioid Hemangioma Matthew R. Lindberg, MD 454 Spindle Cell Hemangioma Michella Whisman, MD and Jerad M. Gardner, MD 458 Intramuscular Angioma Matthew R. Lindberg, MD and Jonathan B. McHugh, MD 462 Hobnail Hemangioma David Cassarino, MD, PhD 464 Acquired Tufted Angioma David Cassarino, MD, PhD 466 Microvenular Hemangioma David Cassarino, MD, PhD 468 Sinusoidal Hemangioma David Cassarino, MD, PhD 470 Glomeruloid Hemangioma David Cassarino, MD, PhD 472 Anastomosing Hemangioma Matthew R. Lindberg, MD 476 Synovial Hemangioma Matthew R. Lindberg, MD 478 Angiomatosis David Lucas, MD 480 Lymphangioma David Cassarino, MD, PhD 484 Massive Localized Lymphedema Matthew R. Lindberg, MD 486 Atypical Vascular Lesion David Lucas, MD INTERMEDIATE (LOCALLY AGGRESSIVE) 488 Kaposiform Hemangioendothelioma David Lucas, MD INTERMEDIATE (RARELY METASTASIZING) 490 Papillary Intralymphatic Angioendothelioma David Cassarino, MD, PhD 492 Retiform Hemangioendothelioma David Cassarino, MD, PhD 494 Composite Hemangioendothelioma David Lucas, MD 496 Pseudomyogenic Hemangioendothelioma Matthew R. Lindberg, MD MALIGNANT 500 Epithelioid Hemangioendothelioma Matthew R. Lindberg, MD and Thomas Mentzel, MD 504 Angiosarcoma Matthew R. Lindberg, MD 510 Kaposi Sarcoma Nicholas Zoumberos, MD, Jerad M. Gardner, MD, and Thomas Mentzel, MD SECTION 11: CHONDROOSSEOUS TUMORS BENIGN 520 Soft Tissue Chondroma David Lucas, MD 526 Synovial Chondromatosis David Lucas, MD MALIGNANT 530 Extraskeletal Osteosarcoma David Lucas, MD 534 Extraskeletal Mesenchymal Chondrosarcoma David Lucas, MD SECTION 12: PERIPHERAL NERVE SHEATH TUMORS BENIGN 540 Solitary Circumscribed Neuroma Nicholas Zoumberos, MD and Jerad M. Gardner, MD 542 Schwannoma Matthew R. Lindberg, MD 556 Neurofibroma Matthew R. Lindberg, MD 566 Perineurioma Matthew R. Lindberg, MD 572 Hybrid Nerve Sheath Tumor Matthew R. Lindberg, MD 576 Granular Cell Tumor Matthew R. Lindberg, MD 582 Dermal Nerve Sheath Myxoma David Lucas, MD 586 Ganglioneuroma Matthew R. Lindberg, MD 590 Neuromuscular Choristoma David Lucas, MD MALIGNANT 592 Malignant Peripheral Nerve Sheath Tumor Matthew R. Lindberg, MD 600 Epithelioid Malignant Peripheral Nerve Sheath Tumor Matthew R. Lindberg, MD 604 Malignant Melanotic Nerve Sheath Tumor Matthew R. Lindberg, MD 606 Ectomesenchymoma Matthew R. Lindberg, MD and Cyril Fisher, MD, DSc, FRCPath SECTION 13: GENITAL STROMAL TUMORS 610 Fibroepithelial Stromal Polyp Matthew R. Lindberg, MD 612 Angiomyofibroblastoma Matthew R. Lindberg, MD 616 Cellular Angiofibroma Matthew R. Lindberg, MD 620 Deep (Aggressive) Angiomyxoma Matthew R. Lindberg, MD SECTION 14: TUMORS OF MESOTHELIAL CELLS BENIGN 626 Adenomatoid Tumor Matthew R. Lindberg, MD 628 Peritoneal Inclusion Cyst Matthew R. Lindberg, MD 630 Well-Differentiated Papillary Mesothelial Tumor David Lucas, MD and Cyril Fisher, MD, DSc, FRCPath MALIGNANT 634 Malignant Mesothelioma Matthew R. Lindberg, MD and Cyril Fisher, MD, DSc, FRCPath SECTION 15: HEMATOPOIETIC TUMORS IN SOFT TISSUE 642 Solitary Extramedullary Plasmacytoma Matthew R. Lindberg, MD 644 Myeloid Sarcoma Matthew R. Lindberg, MD 646 Lymphoma of Soft Tissue Matthew R. Lindberg, MD and Khin Thway, MD, FRCPath SECTION 16: TUMORS OF UNCERTAIN DIFFERENTIATION BENIGN 650 Intramuscular Myxoma Matthew R. Lindberg, MD 654 Juxtaarticular Myxoma Matthew R. Lindberg, MD and Khin Thway, MD, FRCPath 656 Superficial Angiomyxoma Nicholas Zoumberos, MD and Jerad M. Gardner, MD 660 Acral Fibromyxoma Matthew R. Lindberg, MD 664 Pleomorphic Hyalinizing Angiectatic Tumor Matthew R. Lindberg, MD and Cyril Fisher, MD, DSc, FRCPath 668 Aneurysmal Bone Cyst of Soft Tissue Matthew R. Lindberg, MD 670 Ectopic Hamartomatous Thymoma Matthew R. Lindberg, MD INTERMEDIATE (LOCALLY AGGRESSIVE) 674 Hemosiderotic Fibrolipomatous Tumor Matthew R. Lindberg, MD INTERMEDIATE (RARELY METASTASIZING) 676 Atypical Fibroxanthoma David Cassarino, MD, PhD 682 Angiomatoid Fibrous Histiocytoma Matthew R. Lindberg, MD 690 Ossifying Fibromyxoid Tumor Matthew R. Lindberg, MD 696 Myoepithelioma of Soft Tissue Matthew R. Lindberg, MD 704 Phosphaturic Mesenchymal Tumor Matthew R. Lindberg, MD MALIGNANT 706 Synovial Sarcoma Matthew R. Lindberg, MD 718 Epithelioid Sarcoma Matthew R. Lindberg, MD 724 Alveolar Soft Part Sarcoma Matthew R. Lindberg, MD 728 Clear Cell Sarcoma Michella Whisman, MD and Jerad M. Gardner, MD 732 Perivascular Epithelioid Cell Tumor (PEComa) Matthew R. Lindberg, MD 740 Desmoplastic Small Round Cell Tumor Matthew R. Lindberg, MD 746 Extraskeletal Ewing Sarcoma Michella Whisman, MD, Kandi Stallings-Archer, MD, and Cyril Fisher, MD, DSc, FRCPath 752 Extraskeletal Myxoid Chondrosarcoma David Lucas, MD 756 Extrarenal Rhabdoid Tumor Matthew R. Lindberg, MD 760 Intimal Sarcoma Michella Whisman, MD and Jerad M. Gardner, MD SECTION 17: UNDIFFERENTIATED/UNCLASSIFIED SARCOMAS 764 Undifferentiated Pleomorphic Sarcoma Matthew R. Lindberg, MD *768 Undifferentiated Round Cell Sarcoma With CIC::DUX4* Fusion** David Lucas, MD *774 BCOR::CCNB3* Fusion-Positive Sarcoma** David Lucas, MD 778 Undifferentiated Round Cell Sarcoma with EWRS1::NFATC2 Fusion David Lucas, MD *782 Undifferentiated Round Cell Sarcoma with EWRS1::PATZ1* Fusion** Matthew R. Lindberg, MD 786 NTRK-Rearranged Spindle Cell Neoplasms Matthew R. Lindberg, MD 790 GLI1-Rearranged Epithelioid Neoplasms Matthew R. Lindberg, MD SECTION 18: MESENCHYMAL TUMORS OF GASTROINTESTINAL TRACT 796 Benign Neural Gastrointestinal Polyps Matthew R. Lindberg, MD 800 Gastrointestinal Stromal Tumor Matthew R. Lindberg, MD 816 Gastrointestinal Schwannoma Matthew R. Lindberg, MD 818 Gastrointestinal Smooth Muscle Neoplasms Matthew R. Lindberg, MD 822 Inflammatory Fibroid Polyp Matthew R. Lindberg, MD 826 Gangliocytic Paraganglioma Matthew R. Lindberg, MD 828 Plexiform Fibromyxoma Matthew R. Lindberg, MD 832 Malignant Gastrointestinal Neuroectodermal Tumor Matthew R. Lindberg, MD 836 Gastroblastoma Matthew R. Lindberg, MD SECTION 19: OTHER ENTITIES BENIGN 842 Amyloidoma Matthew R. Lindberg, MD 844 Ganglion Cyst Matthew R. Lindberg, MD 846 Tumoral Calcinosis Matthew R. Lindberg, MD 848 Idiopathic Tumefactive Fibroinflammatory Lesions Matthew R. Lindberg, MD 852 Tenosynovitis with Psammomatous Calcifications Matthew R. Lindberg, MD 854 Myxochondroid Metaplasia of Plantar Foot Matthew R. Lindberg, MD 856 Cardiac Myxoma Matthew R. Lindberg, MD 860 Cardiac Fibroma Matthew R. Lindberg, MD 862 Congenital Granular Cell Epulis Matthew R. Lindberg, MD 864 Sinonasal Tract Angiofibroma Matthew R. Lindberg, MD, Lester D. R. Thompson, MD, and Cyril Fisher, MD, DSc, FRCPath 868 Sinonasal Glomangiopericytoma Matthew R. Lindberg, MD and Jonathan B. McHugh, MD 874 Ectopic Meningioma Matthew R. Lindberg, MD 876 Glial Heterotopia Matthew R. Lindberg, MD INTERMEDIATE 878 Paraganglioma Matthew R. Lindberg, MD 886 Peripheral Hemangioblastoma Matthew R. Lindberg, MD 888 Melanotic Neuroectodermal Tumor of Infancy Matthew R. Lindberg, MD 890 Ependymoma of Soft Tissue Matthew R. Lindberg, MD MALIGNANT 892 Metastatic Tumors to Soft Tissue Sites Matthew R. Lindberg, MD 896 Neuroblastoma and Ganglioneuroblastoma Michella Whisman, MD, Jessica M. Comstock, MD, and Cyril Fisher, MD, DSc, FRCPath 906 Extraaxial Soft Tissue Chordoma Michella Whisman, MD and Jerad M. Gardner, MD 908 Embryonal Sarcoma of Liver Matthew R. Lindberg, MD 910 Primary Pulmonary Myxoid Sarcoma David Lucas, MD 916 Biphenotypic Sinonasal Sarcoma Matthew R. Lindberg, MD 920 Spindle Epithelial Tumor With Thymus-Like Elements Matthew R. Lindberg, MD 922 Gynecologic Neoplasms Mimicking Soft Tissue Tumors