Principles of Neonatology

Description:

Written by leading global experts in the field, Principles of Neonatology provides those on the NICU team with clinically focused, evidence-based guidance in an easy-to-access format.  Chapters cover the key topics of greatest and most frequent concern to clinicians treating newborns, delivering current, data-driven management and treatment advice in a single source relevant to the seasoned practitioner, fellow, or trainee. 

Features:

• A highly templated format makes it easy to find exactly the information you need.  
• Lavishly illustrated with photos, radiographs, drawings, and charts and graphs that clarify key concepts in a helpful and accessible way. 
• Evidence-based focus ensures that only the most reliable treatment protocols and clear-cut, data-driven guidance are included. 
• Coverage of all relevant topics in the NICU: skin lesions, congenital anomalies, architecture/development of neonatal intensive care units, pain control, anesthesia for newborn infants, and much more. 
• Ideal for every member of the NICU team: neonatologists, neonatology fellows, residents, and neonatal nurses, as well as all other clinicians working in the NICU, including PAs, occupational therapists, respiratory therapists, and others. 
• An digital version is included with purchase. The digital allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. 

Table Of Contents:

Section 1: Care of the Premature and Critically-Ill Neonate

1 Design of Neonatal Intensive Care Units, 2

Margaret Kuper-Sassé, Cynthia F. Bearer, Dina El-Metwally

2 NICU Environment for Parents and Staff, 7

Angela E. Lee-Winn, Dina El-Metwally, Erica M.S. Sibinga

3 Safe Use of Health Information Technology, 12

Yahya Ethawi, Abbas AlZubaidi, Akhil Maheshwari

4 Pharmacologic Management of Neonatal Pain and Agitation, 18

Christopher McPherson

5 Neonatal Transport, 27

Webra Price-Douglas, Susan J. Dulkerian

6 Radiation Safety in Premature and Critically-Ill Neonates, 33

Sheila Berlin

Section 2: Neonatal Resuscitation and Respiratory Care

7 Placental Transfusion in the Newborn, 38

Sripriya Sundararajan, Renske McFarlane, Heike Rabe

8 Neonatal Resuscitation, 44

Lee Donohue, Ziad Alhassen, Satyan Lakshminrusimha

9 Golden Hour and Thermoregulation, 57

Erin E. Schofield, Lindy W. Winter

10 Oxygen During Postnatal Stabilization, 62

Maximo Vento, Ola D. Saugstad

11 Respiratory Distress Syndrome, 66

Kartikeya Makker, Colby L. Day-Richardson, Mark L. Hudak

12 Invasive and Noninvasive Ventilation Strategies, 78

Vikramaditya Dumpa, Vineet Bhandari

13 Pulmonary Hypertension of the Newborn, 88

Praveen Chandrasekharan, Satyan Lakshminrusimha

14 Bronchopulmonary Dysplasia, 98

Mireille Guillot, Bernard Thébaud

15 Treatment of Apnea of Prematurity, 106

Zeyar Htun, Richard J. Martin

Section 3: Feeding

16 Human Milk, 112

Nitasha Bagga, Kei Lui, Arunas Liubšys, Mohammad M. Rahman, Srijan Singh, Mimi L. Mynak, Akhil Maheshwari

17 Storage and Use of Human Milk in Neonatal Intensive Care Units, 120

Nitasha Bagga, Kei Lui, Arunas Liubšys, Mohammad M. Rahman, Mimi L. Mynak, Akhil Maheshwari

18 Possible Benefits and Risks of Using Probiotics in Neonates, 128

Mohan Pammi, Monika S. Patil, Kristina Reber, Akhil Maheshwari

Section 4: Nutrition

19 Enteral Nutrition, 142

Allison Rohrer, Sarah N. Taylor

20 Parenteral Nutrition in Neonates, 156

Stephanie M. Barr, Laura Cummings

21 Nutrition in Short Bowel Syndrome, 170

Muralidhar H. Premkumar, Alvaro Dendi, Akhil Maheshwari

22 Neonatal Nutrition Assessment, 178

Kera M. McNelis, Tanis R. Fenton

Section 5: Endocrine Disorders

23 Neonatal Hypoglycemia, 193

Winnie Sigal, Diva D. De Leon

24 Infants of Diabetic Mothers, 200

Vinayak Mishra, Kei Lui, Robert L. Schelonka, Akhil Maheshwari, Rajesh Jain

25 Evidence-Based Neonatology: Neonatal Pituitary Hormone Deficiencies, 207

Lauryn Choleva, Mabel Yau, Christopher J. Romero

26 Neonatal Thyroid Disease, 215

Andrew J. Bauer

27 Hypothalamic-Pituitary-Adrenal Axis in Neonates, 222

David W. Cooke, Yasmin Akhtar

28 Disorders of Neonatal Mineral Metabolism and Metabolic Bone Disease, 230

Andrew C. Calabria, Sarah A. Coggins

29 Disorders of Sex Development for Neonatologists, 241

John Fuqua

Section 6: Infections

30 Early-Onset Sepsis, 251

Karen M. Puopolo

31 Late-Onset Sepsis, 257

Dustin D. Flannery, Karen M. Puopolo

32 Neonatal Herpes Simplex Virus Infections, 261

Yahya Ethawi, Steven Garzon, Thierry A.G.M. Huisman, Suresh Boppana, Akhil Maheshwari

33 Postnatal Cytomegalovirus Infection Among Preterm Infants, 268

Sagori Mukhopadhyay, Kristin Weimer

34 Congenital Syphilis, 274

Alvaro Dendi, Helena Sobrero, María Mattos Castellano, Akhil Maheshwari

35 Invasive Fungal Infections in the NICU: Candida, Aspergillosis, and Mucormycosis, 279

David A. Kaufman, Namrita J. Odackal, Hillary B. Liken

Section 7: Cardiac Defects and Dysfunction

36 Congenital Heart Defects, 291

Diana Vargas Chaves, Shazia Bhombal, Ganga Krishnamurthy

37 Cardiac Defects—Anatomy and Physiology, 299

Rune Toms, Rachana Singh

38 Medical and Surgical Management of Critical Congenital Heart Disease, 317

David M. Kwiatkowski

39 Neonatal Arrhythmia and Conduction Abnormalities, 326

Shazia Bhombal, Megan L. Ringle, Yaniv Bar-Cohen

40 Pulmonary Hypertension in Chronic Lung Disease, 336

Megan L. Ringle, Gabriel Altit

41 Hemodynamic Assessment and Management of a Critically Ill Infant, 344

Tai-Wei Wu, Shahab Noori

Section 8: Jaundice, Blood Disorders, and Transfusions

42 A Practical Guide to Evaluating and Treating Severe Neonatal Indirect Hyperbilirubinemia, 351

Timothy M. Bahr

43 Neonatal Anemia, 357

Robert D. Christensen

44 Evidence-Based Neonatal Transfusion Guidelines, 380

Robin K. Ohls

45 Neonatal Thrombocytopenia, 387

Akhil Maheshwari

Section 9: Neurological Disorders

46 Management of Hypoxic-Ischemic Encephalopathy Using Therapeutic Hypothermia, 400

Joanne O. Davidson, Alistair J. Gunn

47 Management of Hypoxic-Ischemic Encephalopathy Using Measures Other Than Therapeutic Hypothermia, 406

Jennifer Burnsed, Raul Chavez-Valdez

48 Management of Encephalopathy of Prematurity, 421

Sandra E. Juul, Niranjana Natarajan, Ulrike Mietzsch

49 Neonatal Seizures, 427

Melisa Carrasco, Carl E. Stafstrom

50 Stroke in Neonates, 438

Ryan J. Felling, Lisa R. Sun

51 Using Biomarkers for Management of Perinatal Brain Injury, 444

Allen D. Everett, Ernest Graham, Melania M. Bembea

52 Intraventricular Hemorrhage and Posthemorrhage Hydrocephalus, 447

Venkat Reddy Kallem, Akhil Maheshwari

53 Management of Neurotrauma, 456

Joaquin Hidalgo, Eric M. Jackson

54 Management of Myelomeningocele and Related Disorders of the Newborn, 462

Mari L. Groves, Jena L. Miller

55 Treating Neonatal Abstinence Syndrome in the Newborn, 470

Jessie R. Maxwell, Sandra Brooks, Tamorah R. Lewis, Jessie Newville, Gabrielle McLemore, Estelle B. Gauda

Section 10: Immunology

56 Neonatal Immunity, 484

Akhil Maheshwari, Sundos Khuder, Shelley M. Lawrence, Robert D. Christensen

57 Immunodeficiency Syndromes Seen During the Neonatal Period, 498

Keyur Donda, Benjamin A. Torres, Jolan Walter, Akhil Maheshwari

Section 11: Kidney

58 Neonatal Acute Kidney Injury, 508

Heidi J. Steflik, David T. Selewski, Alison Kent, Cherry Mammen

59 Renal Replacement Therapy, 519

Julie E. Goodwin, Ashok Kumar, Jorge Fabres, Akhil Maheshwari

60 Neonatal Hypertension, 525

Janis M. Dionne, Joseph T. Flynn

61 Altered Development of the Kidneys and the Urinary Tract, 533

Julie E. Goodwin, Akhil Maheshwari

Section 12: Eye Disorders

62 Retinopathy of Prematurity, 545

Prolima G. Thacker, Michael X. Repka

63 Developmental Anomalies of the Globe and Ocular Adnexa in Neonates, 552

Jefferson J. Doyle, Mireille Jabroun

64 Developmental Anomalies of the Cornea and Iris in Neonates, 560

Rachel R. Milante, Jefferson J. Doyle

65 Cataract and Glaucoma, 570

Rachel R. Milante, Courtney L. Kraus

Section 13: ENT and Auditory Conditions

66 Neonatal Tracheostomy, 577

Jonathan Walsh

67 Stridor and Laryngotracheal Airway Obstruction in Newborns, 582

Elaine O. Bigelow, David E. Tunkel

68 Pierre-Robin Sequence/Cleft Palate-Related Airway Obstruction Seen in Neonates, 592

Anita Deshpande, Mai Nguyen, Steven L. Goudy

69 Congenital Hearing Loss Seen in Neonates, 597

Kavita Dedhia, Albert Park

70 Nasal Obstruction in Newborn Infants, 607

Marisa A. Ryan, David E. Tunkel

Section 14: Orthopedic Conditions

71 Upper Extremity Conditions in the Neonate, 618

Jessica G. Shih, Lahin M. Amlani, Laura Lewallen

72 Newborn Spine Deformities, 624

Alexandra M. Dunham, Paul D. Sponseller

73 Hip and Lower Extremity Deformities, 631

Erin Honcharuk

74 Fractures and Musculoskeletal Infections in the Neonate, 641

Arjun Gupta, Paul D. Sponseller

Section 15: Inborn Errors of Metabolism and Newborn Screening

75 Most Frequently Encountered Inborn Errors of Metabolism, 649

Jubara Alallah, Pankaj B. Agrawal, Alvaro Dendi, Akhil Maheshwari

76 Screening Programs for Early Detection of Inborn Errors of Metabolism in Neonates, 661

Amarilis Sanchez-Valle

Section 16: Genetic Conditions (Including Microarrays, Exome Sequencing)

77 An Overview of Genetic Testing, 671

Wendy K. Chung, John P. Schacht, Haluk Kavus

78 Genetics of Common Birth Defects in Newborns, 677

Shannon N. Nees, Eric Jelin, Wendy K. Chung

79 Common Monogenetic Conditions in Newborns, 690

Christine H. Umandap, Elaine M. Pereira

80 Common Chromosomal Conditions in Newborns, 699

Marisa Gilstrop Thompson, Eric Jelin, Angie Jelin

Section 17: Neonatal Surgical Conditions

81 Necrotizing Enterocolitis, 707

Jennine Weller, Maame E.S. Sampah, Andres J. Gonzalez Salazar, David J. Hackam

82 Extracorporeal Membrane Oxygenation in Neonates, 715

Eric W. Etchill, Alejandro V. Garcia

83 Intestinal Surgery in the Newborn—Atresias, Volvulus, and Everything Else, 720

Ross M. Beckman, Daniel S. Rhee

84 Pulmonary Surgery in the Newborn, 727

Andres J. Gonzalez Salazar, Carley Blevins, Eric Jelin

85 Congenital Anorectal Malformations and Hirschsprung Disease in the Neonate, 738

Isam W. Nasr, Eric W. Etchill

86 Esophageal Surgery in Neonates: Esophageal Atresia, Gastroesophageal Reflux, and Other Congenital Anomalies, 745

Mark L. Kovler, Shaun M. Kunisaki

Section 18: Current State of Neonatal Palliative Care

87 Caring for Families Who Have Previously Endured Multiple Perinatal Losses, 754

Kathryn Grauerholz, Michaelene Fredenburg, Shandeigh N. Berry, DiAnn Ecret

88 Current State of Perinatal Palliative Care: Clinical Practice, Training, and Research, 758

Renee Boss, Sara Munoz-Blanco, Steven Leuthner

89 Serious Communication in the Neonatal Intensive Care Unit: Evidence for Strategies and Training, 765

Stephanie K. Kukora, Naomi T. Laventhal

90 Pain and Symptom Management in Newborns Receiving Palliative and End-of-Life Care, 776

Kelstan Ellis, Brian S. Carter

91 Palliative Care Family Support in Neonatology, 783

Erin R. Currie, Hema Navaneethan, Meaghann S. Weaver

Section 19: Follow-Up

92 Early Diagnosis and Intervention in Neonatal Intensive Care Units, 791

Naveen Jain

93 Early Diagnosis and Intervention—On Neonatal Follow-Up, 797

Naveen Jain

94 Early Detection of Cerebral Palsy, 802

Betsy E. Ostrander, Nathalie L. Maitre, Andrea F. Duncan

95 Use of Neuroimaging to Predict Adverse Developmental Outcomes in High-Risk Infants, 812

Gayatri Athalye-Jape

96 Neurodevelopmental Impairment in Specific Neonatal Disorders, 823

Vinayak Mishra, Brian Sims, Margaret Kuper-Sassé, Akhil Maheshwari

Section 20: Designing Clinical Trials in Neonatology

97 Quality Improvement in Neonatal Care, 833

Colleen A. Hughes Driscoll

98 Neonatal Randomized Controlled Trials, 838

Gerri Baer, Norma Terrin, Donna Snyder, Jonathan M. Davis

99 Designing Clinical Trials in Neonatology—International Trials, 845

Marc Beltempo, Prakesh S. Shah

Section 21: Healthcare Leadership

100 Organization of Neonatal Intensive Care, 851

Prabhu S. Parimi, Guilherme M. Sant’Anna, Alvaro Dendi, Martin Antelo, Sundos J. Khuder, Jargalsaikhan Badarch, Mohammad M. Rahman, Ashok Kumar, Akhil Maheshwari

101 Leadership and Organizational Culture in Healthcare, 856

Prabhu S. Parimi, Jorge Fabres, Yahya Ethawi, Jubara Alallah, Michaelene Fredenburg, Rajesh Jain, Mohammad M. Rahman, Kei Lui, Arunas Liubšys, Mimi L. Mynak, Barton Goldenberg, Giuseppe Buonocore, Akhil Maheshwari

Section 22: Neonatal Dermatology

102 Skin Disorders in Newborn Infants, 862

Shaifali Bhatia, Akhil Maheshwari