Comprehensive Gynecology

 

Description:

With its trademark clear, concise writing style and evidence-based focus, Comprehensive Gynecology, 8th Edition, remains your #1 choice for practical, in-depth coverage of any women’s health issue you’re likely to encounter. It covers all key issues in gynecology, now fully updated to include new information on topics such as laparoscopy and innovations in robotic surgery, reversible contraception, and advancements in treating endometriosis. For residents, specialists, primary care doctors, and other healthcare providers, Comprehensive Gynecology is an easy-to-access source of trusted information for everyday practice.

Includes helpful features such as key references and terms, key points at the end of each chapter, summary boxes for quick reference, and new bolded text to highlight the most important concepts. 

Features newly improved artwork; a more cohesive, easy-to-navigate design throughout; and more clinical algorithms. 

Contains hundreds of illustrations and tables, anatomical figures, radiographs, and photographs, as well as 20 videos that address topics such as Pap smear techniques, hysteroscopic metroplasty, and endometriosis of the bladder. 

Brings you up to date with the latest applications in diagnostic and interventional ultrasound, issues in infertility, the latest research in menopause, and other essential aspects of today's practice.

 

 

Table of Contents:

 

Part I. Basic Science

1.  Fertilization and embryogenesis

Meiosis, fertilization, implantation, embryonic development, and sexual differentiation

The oocyte and meiosis

Fertilization and early cleavage

Implantation

Development of the genitourinary system

Molecular basis of sex differentiation

Acknowledgments

References

2.  Reproductive genetics

Genetic basis of disease

Building blocks of genetics

Genetic pathology

Perinatal genetics

Genetics of reproductive malignancies

Cancer genome sequencing

Ethical considerations of genetic diagnosis

Key references

References

Suggested readings

3.  Reproductive anatomy

External genitalia

Clinical correlations

Internal genitalia

Clinical correlations

Clinical correlations

Clinical correlations

Clinical correlations

Clinical correlations

Vascular system of the pelvis

Clinical correlations

Lymphatic system

Clinical correlations

Innervation of the pelvis

Clinical correlations

Diaphragms and ligaments

Clinical correlations

Nongenital pelvic organs

Clinical correlations

Other structures

Clinical correlations

References

Suggested readings

4.  Reproductive endocrinology

The hypothalamus and GnRH

The anterior pituitary gland and the gonadotropins

The ovaries

Communication within the hypothalamic-pituitary-ovarian endocrine axis

The menstrual cycle

The menstrual cycle and the endometrium

The menstrual cycle and the cervical glands

Assay evaluation

References

Suggested readings

5.  Evidence-based medicine and clinical epidemiology

Introduction to evidence-based medicine

Traditional clinical study design

Comparative effectiveness research

Health services research

New horizons: Value in health care

Key references

References

Suggested readings

6.  Medical-legal risk management

Historical perspective

Reproductive medicine and the courts

Practical insight

Cap strategy

Communication

Anticipation

Preparation

Conclusion

References

Suggested readings

Part II. Comprehensive Evaluation of the Women

7.  History, physical examination, and preventive health care

Direct observations before speaking to the patient (nonverbal clues)

Essence of the gynecologic history

Components of the physical examination

Advocacy, screening, interventions, and referral

Special populations

References

Suggested readings

8.  Interaction of medical diseases and female physiology

Pulmonary disease

Gastrointestinal disease

Hematologic and thrombotic diseases

Central nervous system disease

Mental health issues

Cancer

Summary

Key references

References

9.  Additional considerations in gynecologic care

Depression

Eating disorders

Obesity

Anxiety disorders, obsessive-compulsive disorder, and posttraumatic stress disorder

Psychotropic medications and oral contraceptives

Substance use disorders

“Difficult” patients and challenging clinical encounters

Sexual function and dysfunction

Lesbian, bisexual, and transgender health care

Rape, sexual assault, and intimate partner violence

Grief and loss

Death and dying

Key references

References

Suggested readings

10.  Endoscopy in minimally invasive gynecologic surgery

Introduction

Preoperative decision making

Hysteroscopy

Gynecologic laparoscopy

Hand-assisted laparoscopy

Adnexal pathology

Sterilization

Pelvic inflammatory disease

Oncology

Pelvic prolapse

Complications of laparoscopy

Specimen removal

How we learn: The role of endoscopic simulation

Gynecologic surgery: The triple aim

References

Suggested readings

Part III. General Gynecology

11.  Congenital abnormalities of the female reproductive tract

Ambiguous genitalia

Müllerian anomalies

References

Suggested readings

12.  Pediatric and adolescent gynecology

Gynecologic visit and examination of a child

Accidental genital trauma

References

Suggested readings

13.  Contraception and abortion

Contraception overview

Contraceptive counseling

Contraceptive effectiveness

Emergency contraception

Other contraceptive concerns

Breastfeeding

Induced abortion

Methods of abortion

References

Suggested readings

14.  Menopause and care of the mature woman

Premature ovarian insufficiency

Menopausal transition (perimenopause)

Effects of menopause on various organ systems

Degenerative arthritis

Cardiovascular effects

Cancer risks in postmenopausal women

Disease prevention after menopause

Alternative therapies for menopause

Key references

References

Suggested readings

15.  Breast diseases

Anatomy/embryology

Congenital developmental breast abnormalities

Breast carcinoma

Epidemiology and risks for breast cancer

Demographic associations

Estrogen-related exposure risks

Lifestyle and dietary risk factors

Breast history and breast characteristics

Inherited and familial risks

Radiation exposure

Risk assessment and prevention

Chemoprophylaxis and chemotherapeutic risk reduction

Detection and diagnosis

Ductal carcinoma in situ

Lobular carcinoma in situ

Infiltrating or invasive ductal carcinoma

Infiltrating lobular carcinoma

Inflammatory breast cancer

Paget disease

Genomic profiling

Management

Breast cancer during pregnancy

Surveillance

Key references

References

Suggested readings

16.  Early and recurrent pregnancy loss

Epidemiology

Recurrent pregnancy loss evaluation

Etiology

Chromosomal

Uterine anomalies

Endocrine factors

Immunologic factors

Inherited thrombophilia

Infections

Environmental factors

Male factors

Unexplained recurrent pregnancy loss

Pregnancy loss diagnostic evaluation

Pregnancy loss diagnosis

Bleeding in early pregnancy

Management of early pregnancy loss

Acknowledgment

Key references

References

17.  Ectopic pregnancy

Epidemiology

Mortality

Etiology

Sites of ectopic pregnancy

Histopathology

Symptoms

Signs

Management

Prognosis for subsequent fertility

References

Suggested readings

18.  Benign gynecologic lesions

Introduction

Vulva

Dermatologic diseases

Vagina

Cervix

Uterus

Adenomyosis

Oviduct

Ovary

Key references

References

Suggested readings

19.  Endometriosis

Endometriosis: Overview

Monitoring the course of disease: Are there markers?

Treatment

Endometriosis at other sites

Extra pelvic endometriosis

Key references

References

Suggested readings

20.  Pelvic organ prolapse, abdominal hernias, and inguinal hernias

Abdominal wall hernias

Pelvic organ prolapse

Rectal prolapse

Conclusion

Key references

References

Suggested readings

21.  Lower urinary tract function and disorders

Physiology of micturition

Diagnostic procedures

Lower urinary tract pain: Acute bacterial cystitis, bladder pain syndrome/interstitial cystitis, urethral diverticulum

Urinary incontinence

Urgency urinary incontinence/overactive bladder

Key references

References

Suggested readings

22.  Anal incontinence

Epidemiology of incontinence

Rectovaginal fistulas

References

Suggested readings

23.  Genital tract infections

Infections of the vulva

Vaginitis

Toxic shock syndrome

Cervicitis

Endometritis

Pelvic inflammatory disease

Actinomyces infection

Tuberculosis

References

24.  Preoperative counseling and management

Preoperative history

Physical examination

Laboratory and preoperative diagnostic procedures

Patient education and informed consent

Preoperative preparation

Consultation with anesthesiologist

Perioperative management

Reducing postoperative complications

Chronic anticoagulation and bleeding disorders

Summary

Key references

References

25.  Perioperative management of complications

Postoperative fever

Management of falling hemoglobin

Respiratory complications

Cardiovascular problems

Urinary tract problems

Gastrointestinal complications

Wound complications

Operative site complications

Psychological sequelae

Discharge instructions and postoperative visits

Appendix A

Appendix B

Appendix C

Naloxone per naloxone IV (NARCAN) administration policy

Transition from IV to PO

Breakthrough or procedural pain

Oversedation

Key references

References

Suggested readings

26.  Abnormal uterine bleeding

Causes of abnormal uterine bleeding

Diagnostic approach

Treatment of abnormal uterine bleeding

Management of acute bleeding

Key references

References

Suggested readings

Part IV. Gynecologic Oncology

27.  Molecular oncology in gynecologic cancer

The immunologic response

Molecular oncology

Gynecologic malignancies

Conclusion

Key references

References

28.  Principles of radiation therapy and chemotherapy in gynecologic cancer

Radiation therapy

Chemotherapy

References

Suggested readings

29.  Intraepithelial neoplasia of the lower genital tract (cervix, vagina, vulva)

Introduction

Etiology: Human papillomavirus

Risk factors

Primary prevention: HPV vaccination

Secondary prevention

Colposcopy

Treatment of cervical dysplasia

Vulvar intraepithelial neoplasia

Key references

References

30.  Neoplastic diseases of the vulva and vagina

Premalignant and malignant lesions of the vulva

Vulvar atypias

Malignant conditions

Premalignant and malignant lesions of the vagina

Premalignant disease of the vagina

Malignant disease of the vagina

Tumors of the adult vagina

Vaginal tumors of infants and children

Key references

References

Suggested readings

31.  Malignant diseases of the cervix

Histologic types

Carcinoma of the cervix

Recurrence

References

Suggested readings

32.  Malignant diseases of the uterus

Epidemiology

Endometrial hyperplasia

Endometrial carcinoma

Sarcomas

References

Suggested readings

33.  Malignant diseases of the ovary, fallopian tube, and peritoneum

Familial ovarian cancer

Classification of ovarian neoplasms

Epithelial ovarian neoplasms

Adnexal mass and ovarian cancer

Rare epithelial ovarian cancer subtypes

Small cell carcinoma

Germ cell tumors

Gonadoblastoma (germ cell sex cord–stromal tumor)

Sex cord–stromal tumors

Lipid (lipoid) tumor

Metastatic ovarian tumors

References

Suggested readings

34.  Gestational trophoblastic disease

Hydatidiform mole

Gestational trophoblastic neoplasia

References

Suggested readings

Part V. Reproductive Endocrinology and Infertility

35.  Primary and secondary dysmenorrhea, premenstrual syndrome, and premenstrual dysphoric disorder

Dysmenorrhea

Incidence and epidemiology

Primary dysmenorrhea

Secondary dysmenorrhea: Causes and management

Other structural abnormalities of the reproductive tract

Congenital obstructive anomalies

Nongynecologic causes for pelvic pain

Premenstrual syndrome and premenstrual dysphoric disorder

Key references

References

Suggested readings

36.  Primary and secondary amenorrhea and precocious puberty

Primary and seconday amenorrhea

Physiology leading up to menarche

Primary amenorrhea

Secondary amenorrhea

Precocious puberty

References

Suggested readings

37.  Hyperprolactinemia: Evaluation and management

Physiology

Causes of hyperprolactinemia

Diagnostic techniques

Treatment

References

Suggested readings

38.  Androgen excess in women

Physiology of androgens in women

Causes of androgen excess

The diagnostic approach for women with androgen excess

Treatment of androgen excess

References

Suggested readings

39.  Polycystic ovary syndrome

Polycystic ovary syndrome: Definition

Ovarian morphology

The diagnosis in adolescence

Menstrual irregularity

Androgen excess or hyperandrogenism

Characteristic endocrine findings in polycystic ovary syndrome

Insulin resistance

Antimüllerian hormone in PCOS

Pathophysiologic considerations

Weight gain/obesity and metabolic syndrome

Diabetes

Quality-of-life issues

Cardiovascular concerns

Cancers in polycystic ovary syndrome

Ovarian aging: Polycystic ovary syndrome and menopause

Isolated polycystic ovaries

Treatment of polycystic ovary syndrome

Treatment of subfertility in polycystic ovary syndrome

Metabolic and weight concerns

Key references

References

Suggested readings

40.  Infertility

Infertility and natural conception

Incidence of subfertility and infertility

Infertility and age

Causes of infertility

Diagnostic evaluation

Prognosis of various diagnoses uncovered by the infertility investigation

Treatment of various causes of infertility

Pregnancy outcomes in women treated for infertility

Counseling and emotional support

References

Suggested readings

41.  In vitro fertilization

Specific indications for in vitro fertilization

In vitro fertilization procedure

Risks of in vitro fertilization

Future developments

References

Suggested readings

Index

 

An aparitie	16 Aug. 2021
Autor	David M Gershenson, Gretchen M Lentz, Fidel A Valea, Rogerio A. Lobo
Dimensiuni	21.59 x 27.64 cm
Editura	Elsevier
Format	Hardcover
ISBN	9780323653992
Limba	Engleza
Nr pag	912