Sarcomas: Evidence-based Diagnosis and Management

Sarcomas: Evidence-Based Diagnosis and Management is the most comprehensive clinical reference on sarcomas available to oncologists and trainees. Presenting a compilation of the current knowledge of specific soft tissue and bone sarcomas, this accessible resource on diagnosis and management is the most practical in the market. Led by the world’s foremost sarcomas experts in medical oncology, surgical oncology, radiation oncology, gynecologic oncology, orthopedic surgery, radiology, and pathology, the book addresses the general principles of each major medical discipline, provides details on each major sarcoma subtype, and presents the evidence for standard frontline, adjuvant, and novel treatment approaches such as immunotherapy, cellular therapies, and more.

The book begins with general principles of diagnosis and management for each discipline in the field, covering specialties from medical oncology to radiology. Following the chapters on general principles, are chapters characterizing the most prevalent subtypes of sarcoma including their estimated incidence, common presenting symptoms, diagnostic approach, radiographic features and essential imaging, key diagnostic features, molecular characteristics, approaches to treatment, recommended follow up, the metastatic potential as well as evidence-based therapeutic approaches. Each chapter ends with a summary of caveats, clinical pearls, pitfalls, and solutions as well as a case study from the clinician’s point of view. The book ends with chapters focusing on new approaches to treatment and the development of therapeutics to combat sarcoma using immunotherapy, cellular therapy, and interventional radiology. Numerous tables and disease-based images support the text and provide key information for quick reference. Presenting detailed evidence and authoritative clinical guidance throughout, Sarcomas is a “one-stop” guide for any clinician diagnosing, treating, or managing patients suffering from these heterogenous diseases.

Key Features:

• Provides the standards of care and evidence base for treatment of each major sarcoma subtype
• Covers all new treatment paradigms and FDA approvals
• Includes numerous quick reference tables and high-quality color images
• Presents over 20 practical case studies from leading clinicians in the field
• Purchase includes access to the ebook for use on most mobile devices or computers

Table of Contents:

Copyright

Contributors

Preface

Abbreviations

Acknowledgments

Introduction

I: Epidemiology and General Principles

1: Medical Oncology

2: Surgical Oncology

3: Pathology of Sarcoma

4: Radiation Oncology

5: Surgical Approach and Surgical Reconstruction Options in Treatment of Bone Sarcomas

6: Pediatric Oncology

7: Radiologic Evaluation of Bone and Soft Tissue Sarcoma at Diagnosis and Follow-Up

II: Select Sarcoma Subtypes

8: Leiomyosarcoma

9: Dedifferentiated Liposarcoma

10: Gastrointestinal Stromal Tumor

11: Osteosarcoma

12: Chondrosarcoma

13: Rhabdomyosarcoma

14: Ewing Sarcoma Free

15: Alveolar Soft Part Sarcoma

16: Tenosynovial Giant Cell Tumor/Pigmented Villonodular Synovitis

17: Epithelioid Sarcoma

18: Angiosarcoma

19: Desmoid Tumor

20: Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma/Other Fibrosarcomas

21: Malignant Peripheral Nerve Sheath Tumor

22: Extraskeletal Myxoid Chondrosarcoma

23: Endometrial Stromal Sarcoma

24: Chordoma

25: Myxoid Liposarcoma

26: Perivascular Epithelioid Cell Sarcoma

27: Synovial Sarcoma

III: Other Treatment Approaches

28: Immunotherapy for Sarcoma

29: Cellular Therapy

30: Interventional Radiology