Lanzkowsky's Manual of Pediatric Hematology and Oncology
Produs indisponibil momentan. Pentru comenzi va rugam trimiteti mail la adresa depozit2@prior.ro sau contactati-ne la numarul de telefon 021 210 89 28 Vedeti mai jos alte produse similare disponibile.
Disponibilitate: Acest produs nu este momentan in stoc
Editura: Elsevier
Limba: Engleza
Nr. pagini: 788
Coperta: Hardback
Dimensiuni: 22,4 x 4,3 x 27,7 cm
An aparitie: 2016
Features:
Presents a concise, systematic approach to all pediatric hematologic and oncologic disorders in one manual
Offers an alternative to bigger references which only cover either oncologic or hematologic disorders in twice as many pages
Presents an easy-to-read format: multiple tables, charts, and flow-diagrams for diagnosis and management of pediatric hematologic and oncologic disorders
Includes 2 new chapters and several expanded chapters: Diagnostic, Molecular and Genomic Methodologies for the Hematologist, Transfusion Medicine, Myelodysplasia, Myeloid Leukemias, and Lymphoid Leukemias
Table Of Contents:
Dedication
List of Contributors
About the Editors
Preface to the Sixth Edition
Preface to the Fifth Edition
Preface to the Fourth Edition
Preface to the Third Edition
Preface to the Second Edition
Preface to the First Edition
Introduction: Historic Perspective
Reflection on 60 Years of Progress in Pediatric Hematology-Oncology
Chapter 1. Diagnostic Molecular and Genomic Methodologies for the Hematologist/Oncologist
Abstract
Clinical Molecular and Genomic Methodologies
Interpreting and Evaluating the Results from Clinical Genetic Testing
Further Reading and References
Chapter 2. Hematologic Manifestations of Systemic Illness
Abstract
Hematologic Manifestations of Diseases Related to Various Organs
Chronic Illness
Lead Intoxication
Nutritional Disorders
Bone Marrow Infiltration
Further Reading and References
Chapter 3. Classification and Diagnosis of Anemia in Children
Abstract
Classification and Diagnosis
Further Reading and References
Chapter 4. Lymphadenopathy and Diseases of the Spleen
Abstract
Lymphadenopathy
Diseases of the Spleen
Splenomegaly
Further Reading and References
Chapter 5. Anemia During the Neonatal Period
Abstract
Hemorrhage
Hemolytic Anemia
Failure of Red Cell Production
Anemia of Prematurity
Physiologic Anemia
Diagnostic Approach to Anemia in the Newborn
Further Reading and References
Chapter 6. Iron-Deficiency Anemia
Abstract
Prevalence
Etiologic Factors
Clinical Features
Diagnosis
Stages of Iron Depletion
Differential Diagnosis
Treatment
Further Reading and References
Chapter 7. Megaloblastic Anemia
Abstract
Vitamin B12 (Cobalamin) Deficiency
Folic Acid Deficiency
Clinical Features of Cobalamin and Folate Deficiency
Diagnosis of Cobalamin and Folate Deficiency
Treatment
Further Reading and References
Chapter 8. Bone Marrow Failure
Abstract
Aplastic Anemia
Acquired Aplastic Anemia
Inherited Bone Marrow Failure Syndromes
Fanconi Anemia
Dyskeratosis Congenita
Congenital Aplastic Anemias of Unknown Inheritance
Diamond–Blackfan Anemia (Congenital Pure Red Cell Aplasia)
Transient Erythroblastopenia of Childhood
Congenital Dyserythropoietic Anemia
Sideroblastic Anemias (Mitochondrial Diseases with Bone Marrow Failure Syndromes)
Severe Congenital Neutropenia and Kostmann Syndrome
Reticular Dysgenesis
Further Reading and References
Chapter 9. General Considerations of Hemolytic Diseases, Red Cell Membrane, and Enzyme Defects
Abstract
Clinical Features of Hemolytic Disease
Laboratory Findings
Membrane Defects
Paroxysmal Nocturnal Hemoglobinuria
Enzyme Defects
Further Reading and References
Chapter 10. Extracorpuscular Hemolytic Anemia
Abstract
Immune Hemolytic Anemia
NonImmune Hemolytic Anemia
Further Reading and References
Chapter 11. Hemoglobinopathies
Abstract
Sickle Cell Disease
Thalassemias
Management of the Acutely Ill Thalassemic Patient
Further Reading and References
Chapter 12. Polycythemia
Abstract
Polycythemia (Erythrocytosis) in the Newborn
Polycythemia in Childhood
Polycythemia Vera
Primary Familial and Congenital Polycythemia
Congenital Polycythemia Due to Altered Hypoxia Sensing with Normal P50
Congenital Polycythemia Due to Altered Hypoxia Sensing with Decreased P50
Other Causes of Polycythemia
Diagnostic Approach
Further Reading and References
Chapter 13. Disorders of White Blood Cells
Abstract
Quantitative Disorders of Leukocytes
Decreased Production or Intrinsic Defects of Neutrophils
Increased Destruction or Extrinsic Defects of Neutrophils
Immune Neutropenia
NonImmune Neutropenia
Eosinophils
Lymphocytes
Disorders of Leukocyte Function
Disorders of Adhesion and Chemotaxis
Disorders of Neutrophil Granules
Disorders of Oxidative Metabolism
Neutrophil Production and Destruction in Newborn Infants
Neutrophil Function in the Newborn
Further Reading and References
Chapter 14. Disorders of Platelets
Abstract
Thrombocytopenia in the Newborn
Inherited Thrombocytopenias
Immune Thrombocytopenic Purpura (ITP)
Other Causes of Thrombocytopenia
Thrombocytosis
Qualitative Platelet Disorders
Acquired Platelet Disorders
Nonthrombocytopenic Purpura
Further Reading and References
Chapter 15. Disorders of Coagulation
Abstract
Hemostatic Disorders
Hemostasis in the Newborn
Detection of Hemostatic Defects
Acquired Coagulation Factor Disorders
Inherited Coagulation Factor Disorders
von Willebrand Disease
Rare Coagulation Factor Disorders (FII, V, VII, X, XI, XIII, Fibrinogen Deficiencies)
Thrombotic Disorders
Venous Thrombosis
Arterial Thrombosis
Antiphospholipid Antibody Syndrome
Hereditary Thrombotic Disorders
Thrombotic Disorders in Newborns
Antithrombotic Agents
Antithrombotic Therapy in Special Conditions
Further Reading and References
Chapter 16. Lymphoproliferative Disorders
Abstract
Lymphoproliferative Disorders
Further Reading and References
Chapter 17. Myelodysplastic Syndromes and Myeloproliferative Disorders
Abstract
Myelodysplastic Syndromes
Juvenile Myelomonocytic Leukemia
Myeloproliferative Neoplasms
CML, BCR–ABL1 Positive
Essential Thrombocythemia and Polycythemia Vera
Primary Myelofibrosis
Further Reading and References
Chapter 18. Acute Lymphoblastic Leukemia
Abstract
Incidence of ALL
Etiology
Clinical Features of ALL
Prognostic Factors
Treatment
Infant Leukemia
Philadelphia-Positive ALL
Down Syndrome and ALL
Relapse in Children with ALL
Future Drugs in ALL Therapy
Further Reading and References
Chapter 19. Acute Myeloid Leukemia
Abstract
Incidence and Epidemiology
Etiology and Predisposing Conditions
Clinical Features
Diagnosis
Classification of AML
Treatment
Novel Therapeutic Approaches
Acute Promyelocytic Leukemia
AML Special Subgroups
Further Reading and References
Chapter 20. Histiocytosis Syndromes
Abstract
Langerhans Cell Histiocytosis
Other Histiocytic Disorders
Macrophage Mediated Disorders
Further Reading and References
Chapter 21. Hodgkin Lymphoma
Abstract
Etiology and Epidemiology
Risk Factors
Biology
Pathology
Clinical Presentation
Diagnostic Evaluation and Staging
Prognostic Factors
Treatment
Long-Term Complications
Follow-Up Evaluations
Further Reading and References
Chapter 22. Non-Hodgkin Lymphoma
Abstract
Introduction
Incidence and Epidemiology
Pathologic Classification
Clinical Features
Diagnosis
Staging
Prognosis
Management
Lymphoblastic Lymphoma
B Lineage NHL
Further Reading and References
Chapter 23. Central Nervous System Malignancies
Abstract
Epidemiology
Pathology
Clinical Manifestations
Genetic Syndromes Associated with Pediatric Brain Tumors
Diagnostic Evaluation
Treatment
Astrocytomas
Medulloblastoma
Relapsed Medulloblastoma
Brain Stem Tumors
Ependymomas
Optic Glioma
Craniopharyngiomas
Intracranial Germ Cell Tumors
Malignant Brain Tumors in Infants and Children Less Than 3 Years of Age
Further Reading and References
Chapter 24. Neuroblastoma
Abstract
Epidemiology
Predisposition
Pathology and Biology
Clinical Features
Diagnosis and Staging
Treatment
Prognosis, Risk Stratification, and Therapy
Post-Therapy Monitoring
Special Treatment Considerations
Neuroblastoma in the Adolescent and Young Adult
Further Reading and References
Chapter 25. Renal Tumors
Abstract
Wilms’ Tumor
Nephroblastomatosis
Congenital Mesoblastic Nephroma
Clear Cell Sarcoma of the Kidney
Rhabdoid Tumor of the Kidney
Renal Cell Carcinoma
Further Reading and References
Chapter 26. Rhabdomyosarcoma and Other Soft-Tissue Sarcomas
Abstract
Incidence and Epidemiology
Pathologic and Genetic Classification
Clinical Features
Diagnostic Evaluation
Staging
Prognosis
Treatment
Follow-Up After Completion of Therapy
Recurrent Disease
Future Perspectives
Further Reading and References
Chapter 27. Malignant Bone Tumors
Abstract
Osteosarcoma
Ewing Sarcoma Family of Tumors
Other Bone Tumors
Further Reading and References
Chapter 28. Retinoblastoma
Abstract
Incidence
Classification
13q Deletion Syndrome
Risk for Second Malignant Neoplasms
Pathology
Clinical Features
Diagnostic Procedures
Treatment
Posttreatment Management
Future Perspectives
Further Reading and References
Chapter 29. Germ Cell Tumors
Abstract
Incidence
Pathology
Clinical Features
Diagnostic Evaluation
Tumor Markers
Staging
Treatment
Further Reading and References
Chapter 30. Hepatic Tumors
Abstract
Incidence
Epidemiology
Pathology
Clinical Features
Diagnostic Evaluation
Staging
Treatment
Follow-up
Prognosis
Further Reading and References
Chapter 31. Hematopoietic Stem Cell Transplantation
Abstract
Allogeneic Stem Cell Transplantation
HSC Sources, Collection, and Manipulation
Engraftment
Complications of HSCT
Late Sequelae of Stem Cell Transplantation
Further Reading and References
Chapter 32. Management of Oncologic Emergencies
Abstract
Metabolic Emergencies
Cardiothoracic Emergencies
Abdominal Emergencies
Renal Emergencies
Neurologic Emergencies
Endocrine Emergencies
Treatment-Associated Emergencies
Further Reading and References
Chapter 33. Supportive Care of Patients with Cancer
Abstract
Management of Infectious Complications
Infection Prophylaxis
Recognition and Management of Nausea and Vomiting
Mucositis
Pain Management
Nutritional Status of the Oncology Patient
Utilization of Hematopoietic Growth Factors
Management of Acute Radiation Side Effects
Management of CVCs
Posttreatment Immunizations
Palliative Care
Further Reading and References
Chapter 34. Evaluation, Investigations, and Management of Late Effects of Childhood Cancer
Abstract
Musculoskeletal System
Cardiovascular System
Respiratory System
Central Nervous System
Endocrine System
Genitourinary System
Ocular System
Auditory System
Gastrointestinal System
Immunologic System
Obesity
Second Malignant Neoplasms
Psychosocial Issues
Further Reading and References
Chapter 35. Psychosocial Aspects of Cancer for Children and Their Families
Abstract
Time of Diagnosis
Treatment Initiation
Illness Stabilization
During Relapses and Recurrences
Treatment Outcomes: The Unsuccessful Course
Treatment Outcomes: The Successful Course
Conclusion
Further Reading and References
Chapter 36. Blood Banking Principles and Practices
Abstract
Introduction
Donor Selection and Collection
Component Preparation
Blood Component Modifications
Special Pediatric Population Needs
Administration
Summary
Further Reading and References
Appendix 1. Hematological Reference Values
Fetal and Cord Blood Hematologic Value
Red Cell Values and Related Serum Values
White Cell Values
Platelet Values
Coagulation Values
Bone Marrow Cells
Appendix 2. Biological Tumor Markers
Index
An aparitie | 2016 |
Autor | Philip Lanzkowsky, Jeffrey M. Lipton , Jonathan D. Fish |
Dimensiuni | 22,4 x 4,3 x 27,7 cm |
Editura | Elsevier |
Format | Hardback |
ISBN | 9780128013687 |
Limba | Engleza |
Nr pag | 788 |
-
1,45900 lei 1,31000 lei
Clientii ebookshop.ro nu au adaugat inca opinii pentru acest produs. Fii primul care adauga o parere, folosind formularul de mai jos.